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Showing papers by "Atsushi Takahashi published in 2008"


Journal ArticleDOI
TL;DR: It is suggested that the common genetic variation within TERT may contribute to the risk of sporadic IFP in the Japanese population.
Abstract: In order to identify a gene(s) susceptible to idiopathic pulmonary fibrosis (IPF), we conducted a genome-wide association (GWA) study by genotyping 159 patients with IPF and 934 controls for 214 508 tag single-nucleotide polymorphisms (SNPs). We further evaluated selected SNPs in a replication sample set (83 cases and 535 controls) and found a significant association of an SNP in intron 2 of the TERT gene (rs2736100), which encodes a reverse transcriptase that is a component of a telomerase, with IPF; a combination of two data sets revealed a p value of 2.9 x 10(-8) (GWA, 2.8 x 10(-6); replication, 3.6 x 10(-3)). Considering previous reports indicating that rare mutations of TERT are found in patients with familial IPF, we suggest that the common genetic variation within TERT may contribute to the risk of sporadic IFP in the Japanese population.

221 citations


Journal ArticleDOI
TL;DR: In this article, a high-silica chabazite with a Si/Al ratio of ca. 17 was obtained by the hydrothermal conversion of FAU zeolite used as a crystalline si/Al source in benzyltrime.
Abstract: A highly crystalline and pure high-silica chabazite zeolite with a Si/Al ratio of ca. 17 was obtained by the hydrothermal conversion of FAU zeolite used as a crystalline Si/Al source in benzyltrime...

82 citations


Journal ArticleDOI
TL;DR: In this paper, the adsorption and thermal reactivity of NO and CO and the kinetics of NO reduction with CO on Ir surfaces were studied using X-ray photoelectron spectroscopy, polarization modulation infrared reflection absorption spectrograph, and temperature programmed desorption.

27 citations


Patent
11 Jul 2008
TL;DR: In this article, a method for producing a lower olefin by an ethanol conversion reaction was proposed, by using a catalyst carrying a group 4 metal in the periodic table on aluminosilicate having an MFI structure.
Abstract: PROBLEM TO BE SOLVED: To provide a method for producing a lower olefin by an ethanol conversion reaction by which the lower olefin such as ethylene and propylene can be produced in a high yield and high selectivity so as to be stable over a long period by carrying out the conversion reaction using ethanol as a raw material. SOLUTION: Ethylene and propylene of the lower olefins can be produced in a high yield and high selectivity and stably over the long period by using a catalyst carrying a group 4 metal in the periodic table on aluminosilicate having an MFI structure. COPYRIGHT: (C)2010,JPO&INPIT

6 citations


Patent
21 Mar 2008
TL;DR: In this article, the authors proposed an updating method of control board for replacing the control unit 3 of the control board 1 containing the controller unit 3 for plant equipment with a new control unit N3 by mounting various electrical components in the housing 2 of the controller board which is installed on a channel base 4 fixed to the floor surface G comprises a first step of separating and removing an existing control unit from an external circuit, a second step of mounting a new controller unit N 3 on an updating control unit mounting rack 6 prepared anew, a third step of fixing a rack fixing base 7
Abstract: PROBLEM TO BE SOLVED: To solve the matter that the facility cost increases and the function shut-down and update periods of a control board are prolonged at the time of update in an update work where the housing of the control board and a control unit are exchanged collectively. SOLUTION: A updating method of control board for replacing the control unit 3 of the control board 1 containing the control unit 3 for plant equipment with a new control unit N3 by mounting various electrical components in the housing 2 of the control board which is installed on a channel base 4 fixed to the floor surface G comprises a first step of separating and removing an existing control unit 3 mounted on an existing control unit mounting rack 2 -2 in the housing 2 of the control board from an external circuit, a second step of mounting a new control unit N3 on an updating control unit mounting rack 6 prepared anew, a third step of fixing a rack fixing base 7 to the existing channel base 4, a fourth step of mounting the updating control unit mounting rack 6 on the rack fixing base 7, and a fifth step of connecting the new control unit N3 and the external circuit after the fourth step. COPYRIGHT: (C)2010,JPO&INPIT

5 citations