T
Taisei Mushiroda
Researcher at University of Tokyo
Publications - 164
Citations - 6870
Taisei Mushiroda is an academic researcher from University of Tokyo. The author has contributed to research in topics: Genome-wide association study & Single-nucleotide polymorphism. The author has an hindex of 43, co-authored 150 publications receiving 5792 citations.
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Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population
Takeshi Ozeki,Taisei Mushiroda,Amara Yowang,Atsushi Takahashi,Michiaki Kubo,Yuji Shirakata,Zenro Ikezawa,Masafumi Iijima,Tetsuo Shiohara,Koji Hashimoto,Naoyuki Kamatani,Yusuke Nakamura +11 more
TL;DR: The data presented here have indicated that DIHS is clinically distinguished from SJS and TEN, and should provide useful information for making a decision of individualized medication of anticonvulsants.
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Overview of the BioBank Japan Project: Study design and profile
Akiko Nagai,Makoto Hirata,Yoichiro Kamatani,Kaori Muto,Koichi Matsuda,Yutaka Kiyohara,Toshiharu Ninomiya,Akiko Tamakoshi,Zentaro Yamagata,Taisei Mushiroda,Yoshinori Murakami,Koichiro Yuji,Yoichi Furukawa,Hitoshi Zembutsu,Toshihiro Tanaka,Yozo Ohnishi,Yusuke Nakamura,Michiaki Kubo +17 more
TL;DR: This report describes the study design and profile of BBJ participants who were registered during the first 5-year period of the project, and concludes that the BBJ Project has constructed the infrastructure for genomic research for various common diseases.
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Genetic variants associated with warfarin dose in African- American individuals: a genome-wide association study
Minoli A. Perera,Larisa H. Cavallari,Nita A. Limdi,Eric R. Gamazon,Anuar Konkashbaev,Roxana Daneshjou,Anna Pluzhnikov,Dana C. Crawford,Jelai Wang,Nianjun Liu,Nicholas P. Tatonetti,Stephane Bourgeois,Harumi Takahashi,Yukiko Bradford,Benjamin Burkley,Robert J. Desnick,Jonathan L. Halperin,Sherief Khalifa,Taimour Y. Langaee,Steven A. Lubitz,Edith A. Nutescu,Matthew T. Oetjens,Mohamed H. Shahin,Shitalben R. Patel,Hersh Sagreiya,Matthew Tector,Karen E. Weck,Mark J. Rieder,Stuart A. Scott,Alan H.B. Wu,James K. Burmester,Mia Wadelius,Panos Deloukas,Michael J. Wagner,Taisei Mushiroda,Michiaki Kubo,Dan M. Roden,Nancy J. Cox,Russ B. Altman,Teri E. Klein,Yusuke Nakamura,Julie A. Johnson +41 more
TL;DR: A novel CYP2C single nucleotide polymorphism exerts a clinically relevant effect on warfarin dose in African Americans, independent of CYP 2C9*2 and CYP9*3, and incorporation of this variant into pharmacogenetic dosing algorithms could improve warFarin dose prediction in this population.
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A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis.
Taisei Mushiroda,Sukanya Wattanapokayakit,Atsushi Takahashi,Toshihiro Nukiwa,Shouji Kudoh,T. Ogura,H Taniguchi,Michiaki Kubo,Naoyuki Kamatani,Yusuke Nakamura +9 more
TL;DR: It is suggested that the common genetic variation within TERT may contribute to the risk of sporadic IFP in the Japanese population.
Journal ArticleDOI
Significant Effect of Polymorphisms in CYP2D6 and ABCC2 on Clinical Outcomes of Adjuvant Tamoxifen Therapy for Breast Cancer Patients
Kazuma Kiyotani,Taisei Mushiroda,Chiyo K. Imamura,Naoya Hosono,Tatsuhiko Tsunoda,Michiaki Kubo,Yusuke Tanigawara,David A. Flockhart,Zeruesenay Desta,Todd C. Skaar,Fuminori Aki,Koichi Hirata,Yuichi Takatsuka,Minoru Okazaki,Shozo Ohsumi,Takashi Yamakawa,Mitsunori Sasa,Yusuke Nakamura,Hitoshi Zembutsu +18 more
TL;DR: In this paper, the effects of polymorphisms in transporter genes and CYP2D6 to clinical outcome of patients receiving tamoxifen were investigated using the Kaplan-Meier method and Cox regression analysis.