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Aude Le Breton
Researcher at Université catholique de Louvain
Publications - 3
Citations - 3709
Aude Le Breton is an academic researcher from Université catholique de Louvain. The author has contributed to research in topics: Cancer & Peptidomimetic. The author has an hindex of 3, co-authored 3 publications receiving 3139 citations.
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PLGA-based nanoparticles: An overview of biomedical applications
Fabienne Danhier,Eduardo Ansorena,Joana M. Silva,Joana M. Silva,Régis Coco,Aude Le Breton,Véronique Préat +6 more
TL;DR: This review presents why PLGA has been chosen to design nanoparticles as drug delivery systems in various biomedical applications such as vaccination, cancer, inflammation and other diseases.
Journal ArticleDOI
RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosis.
TL;DR: This review aims to particularly highlight the position of RGD-based nanoparticles in cancer therapy and imaging and the binding of the RGD peptide to this integrin.
Journal ArticleDOI
Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors.
Romain Boidot,Frédérique Végran,Aline Meulle,Aude Le Breton,Chantal Dessy,Pierre Sonveaux,Sarab Lizard-Nacol,Olivier Feron +7 more
TL;DR: MCT1 is identified as a target for p53 repression and it is suggested that MCT1 elevation in p53-deficient tumors allows them to adapt to metabolic needs by facilitating lactate export or import depending on the glucose availability.