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Aurelia Dinut

Researcher at French Institute of Health and Medical Research

Publications -  6
Citations -  600

Aurelia Dinut is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Sorafenib & Population. The author has an hindex of 3, co-authored 6 publications receiving 398 citations.

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Efficacy and safety of selective internal radiotherapy with yttrium-90 resin microspheres compared with sorafenib in locally advanced and inoperable hepatocellular carcinoma (SARAH): an open-label randomised controlled phase 3 trial

Valérie Vilgrain, +111 more
- 01 Dec 2017 - 
TL;DR: SarAH was a multicentre, open-label, randomised, controlled, investigator-initiated, phase 3 trial done at 25 centres specialising in liver diseases in France to compare the efficacy and safety of sorafenib to that of selective internal radiotherapy in patients with hepatocellular carcinoma.
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Rivaroxaban vs Dalteparin in Cancer-Associated Thromboembolism: A Randomized Trial.

TL;DR: In this paper, a randomized open-label non-inferiority trial was conducted to evaluate the effectiveness of direct oral anticoagulants (DOACs) compared to low-molecular-weight heparin for treating cancer-associated venous thromboembolism (VTE).
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VESPRO: An Individual Patient Data Prospective Meta-Analysis of Selective Internal Radiation Therapy Versus Sorafenib for Advanced, Locally Advanced, or Recurrent Hepatocellular Carcinoma of the SARAH and SIRveNIB Trials

TL;DR: This meta-analysis of the SIRveNIB and SARAH randomized trials will allow the effect of the interventions to be explored with improved reliability/precision with respect to prespecified patient and intervention-level characteristics and Pooling of toxicity results will allow for robust safety profiles to be established for both therapies.
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From prospective clinical trial to reducing social inequalities in health: The DESSEIN trial, concept and design of a multidisciplinary study in precarious patients with breast cancer.

TL;DR: This study aims to evaluate the impact of precariousness on care pathways, treatment and recovery phase according to a multidisciplinary analysis and provide a better understanding of how contextual factors, combined with individual factors, can influence the course of health and thus the stage of the disease at diagnosis.