L
Laurent Castera
Researcher at University of Paris
Publications - 232
Citations - 14382
Laurent Castera is an academic researcher from University of Paris. The author has contributed to research in topics: Transient elastography & Cirrhosis. The author has an hindex of 56, co-authored 232 publications receiving 10435 citations. Previous affiliations of Laurent Castera include University of Bordeaux & University of Caen Lower Normandy.
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Journal ArticleDOI
A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement.
Mohammed Eslam,Philip N. Newsome,Shiv Kumar Sarin,Quentin M. Anstee,Giovanni Targher,Manuel Romero-Gómez,Shira Zelber-Sagi,Vincent Wai-Sun Wong,Jean-François Dufour,Jörn M. Schattenberg,Takumi Kawaguchi,Marco Arrese,Luca Valenti,Gamal Shiha,Claudio Tiribelli,Hannele Yki-Järvinen,Jian-Gao Fan,Henning Grønbæk,Yusuf Yilmaz,Helena Cortez-Pinto,Claudia P. Oliveira,Pierre Bedossa,Leon A. Adams,Ming-Hua Zheng,Yasser Fouad,Wah-Kheong Chan,Nahum Méndez-Sánchez,Sang Hoon Ahn,Laurent Castera,Elisabetta Bugianesi,Vlad Ratziu,Jacob George +31 more
TL;DR: A panel of international experts from 22 countries propose a new definition of metabolic-dysfunction-associated fatty liver disease that is both comprehensive yet simple for the diagnosis of MAFLD and is independent of other liver diseases.
Journal ArticleDOI
Noninvasive Assessment of Liver Disease in Patients With Nonalcoholic Fatty Liver Disease.
TL;DR: The current state of the noninvasive assessment of liver disease in NAFLD is summarized, and an expert synthesis of how these nonin invasive tools could be utilized in clinical practice is provided.
Journal ArticleDOI
Efficacy and safety of selective internal radiotherapy with yttrium-90 resin microspheres compared with sorafenib in locally advanced and inoperable hepatocellular carcinoma (SARAH): an open-label randomised controlled phase 3 trial
Valérie Vilgrain,Valérie Vilgrain,Helena Pereira,Eric Assenat,Boris Guiu,Alina Diana Ilonca,Georges-Philippe Pageaux,Annie Sibert,Mohamed Bouattour,Rachida Lebtahi,Wassim Allaham,Hélène Barraud,Valérie Laurent,Elodie Mathias,Jean-Pierre Bronowicki,Jean-Pierre Tasu,Rémy Perdrisot,Christine Silvain,René Gerolami,Olivier Mundler,Jean-François Seitz,Vincent Vidal,Christophe Aubé,Frédéric Oberti,Olivier Couturier,Isabelle Brenot-Rossi,Jean-Luc Raoul,Anthony Sarran,Charlotte Costentin,Emmanuel Itti,Alain Luciani,Alain Luciani,René Adam,Maïté Lewin,Didier Samuel,Maxime Ronot,Maxime Ronot,Aurelia Dinut,Laurent Castera,Laurent Castera,Gilles Chatellier,Gilles Chatellier,Elisabeth Delhom Christol,Alina D. Ilonca,Julie Lonjon,Mohamed Abdel-Rehim,Arnaud Dieudonné,Christophe Bazin,Carine Chagneau-Derrode,Patrick Borentain,Antoine Bouvier,Laurent Vervueren,Julia Chalaye,Hicham Kobeiter,Julien Edeline,Etienne Garin,Yan Rolland,Isabelle Archambeaud,T. Eugène,Eric Frampas,Christophe Cassinotto,Martine Guyot,Jean-Baptiste Hiriart,Bruno Lapuyade,Julien Vergniol,Philippe Bachellier,Julien Detour,Bernard Duclos,Michel Greget,Francois Habersetzer,Alessio Imperiale,Philippe Merle,Agnès Rode,Julie Morvan,Eric Nguyen-Khac,Thierry Yzet,G. Baudin,Patrick Chevallier,Abakar Mahamat,Thierry Piche,Micheline Razzouk,Patrick Hillon,Romaric Loffroy,Michel Toubeau,Julie Vincent,Gabriele Barabino,Nadia Bouarioua,Muriel Cuilleron,Marie Ecochard,Nathalie Prevot-Bitot,Vincent Leroy,J. Roux,Christian Sengel,Valérie Bourcier,Nathalie Ganne-Carrié,Olivier Seror,Sylvie Costo,Thong Dao,Jean-Pierre Pelage,Jérôme Dumortier,Francesco Giammarile,Pierre-Jean Valette,Nadia Ghazzar,Olivier Pellerin,Julien Taieb,Pierre Weinmann,Alexandra Heurgue-Berlot,Claude Marcus,Daniele Sommacale,Maria-Angéla Castilla-Lièvre,Sophie Maitre,Lysiane Marthey +111 more
TL;DR: SarAH was a multicentre, open-label, randomised, controlled, investigator-initiated, phase 3 trial done at 25 centres specialising in liver diseases in France to compare the efficacy and safety of sorafenib to that of selective internal radiotherapy in patients with hepatocellular carcinoma.
Journal ArticleDOI
EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis – 2021 update
Annalisa Berzigotti,Emmanouil Tsochatzis,Jérôme Boursier,Laurent Castera,Nora Cazzagon,Mireen Friedrich-Rust,Salvatore Petta,Maja Thiele +7 more
TL;DR: In this article, the authors provide the latest update to the EASL Clinical Practice Guidelines on the use of non-invasive tests for the evaluation of liver disease severity and prognosis.
Journal ArticleDOI
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk
Fergus J. Couch,Xianshu Wang,Lesley McGuffog,Andy C. H. Lee,Curtis Olswold,Karoline Kuchenbaecker,Penny Soucy,Zachary S. Fredericksen,Daniel Barrowdale,Joe Dennis,Mia M. Gaudet,Ed Dicks,Matthew L. Kosel,Sue Healey,Olga M. Sinilnikova,Adam M. Lee,Francois Bacot,Daniel Vincent,Frans B. L. Hogervorst,Susan Peock,Dominique Stoppa-Lyonnet,Anna Jakubowska,Paolo Radice,Rita K. Schmutzler,Susan M. Domchek,Marion Piedmonte,Christian F. Singer,Eitan Friedman,Mads Thomassen,Thomas Hansen,Susan L. Neuhausen,Csilla Szabo,Ignacio Blanco,Mark H. Greene,Beth Y. Karlan,Judy Garber,Catherine M. Phelan,Jeffrey N. Weitzel,Marco Montagna,Edith Olah,Irene L. Andrulis,Andrew K. Godwin,Drakoulis Yannoukakos,David E. Goldgar,Trinidad Caldés,Heli Nevanlinna,Ana Osorio,Mary Beth Terry,Mary B. Daly,Elizabeth J. van Rensburg,Ute Hamann,Susan J. Ramus,Amanda E. Toland,Maria A. Caligo,Olufunmilayo I. Olopade,Nadine Tung,Kathleen Claes,Mary S. Beattie,Melissa C. Southey,Evgeny N. Imyanitov,Marc Tischkowitz,Ramunas Janavicius,Esther M. John,Ava Kwong,Orland Diez,Judith Balmaña,Rosa B. Barkardottir,Banu Arun,Gad Rennert,Soo Hwang Teo,Patricia A. Ganz,Ian G. Campbell,Annemarie H. van der Hout,Carolien H.M. van Deurzen,Caroline Seynaeve,Encarna B. Gomez Garcia,Flora E. van Leeuwen,Hanne Meijers-Heijboer,Johannes J. P. Gille,Margreet G. E. M. Ausems,Marinus J. Blok,Marjolijn J. L. Ligtenberg,Matti A. Rookus,Peter Devilee,Senno Verhoef,Theo A. M. van Os,Juul T. Wijnen,Debra Frost,Steve Ellis,Elena Fineberg,Radka Platte,D. Gareth Evans,Louise Izatt,Rosalind A. Eeles,Julian Adlard,Diana Eccles,Jackie Cook,Carole Brewer,Fiona Douglas,Shirley Hodgson,Patrick J. Morrison,Lucy Side,Alan Donaldson,C. E. Houghton,Mark T. Rogers,Huw Dorkins,Jacqueline Eason,Helen Gregory,Emma McCann,Alex Murray,Alain Calender,Agnès Hardouin,Pascaline Berthet,Capucine Delnatte,Catherine Noguès,Christine Lasset,Claude Houdayer,Dominique Leroux,Etienne Rouleau,Fabienne Prieur,Francesca Damiola,Hagay Sobol,Isabelle Coupier,Laurence Venat-Bouvet,Laurent Castera,Marion Gauthier-Villars,Mélanie Léoné,Pascal Pujol,Sylvie Mazoyer,Yves-Jean Bignon,Elżbieta Złowocka-Perłowska,Jacek Gronwald,Jan Lubinski,Katarzyna Durda,Katarzyna Jaworska,Tomasz Huzarski,Amanda B. Spurdle,Alessandra Viel,Bernard Peissel,Bernardo Bonanni,Giulia Melloni,Laura Ottini,Laura Papi,Liliana Varesco,Maria Grazia Tibiletti,Paolo Peterlongo,Sara Volorio,Siranoush Manoukian,Valeria Pensotti,Norbert Arnold,Christoph Engel,Helmut Deissler,Dorothea Gadzicki,Andrea Gehrig,Karin Kast,Kerstin Rhiem,Alfons Meindl,Dieter Niederacher,Nina Ditsch,Hansjoerg Plendl,Sabine Preisler-Adams,Stefanie Engert,Christian Sutter,Raymonda Varon-Mateeva,Barbara Wappenschmidt,Bernhard H. F. Weber,Brita Arver,Marie Stenmark-Askmalm,Niklas Loman,Richard Rosenquist,Zakaria Einbeigi,Katherine L. Nathanson,Timothy R. Rebbeck,Stephanie V. Blank,David E. Cohn,Gustavo C. Rodriguez,Laurie Small,Michael Friedlander,Victoria L. Bae-Jump,Anneliese Fink-Retter,Christine Rappaport,Daphne Gschwantler-Kaulich,Georg Pfeiler,Muy-Kheng Tea,Noralane M. Lindor,Bella Kaufman,Shani Shimon Paluch,Yael Laitman,Anne-Bine Skytte,Anne-Marie Gerdes,Inge Søkilde Pedersen,Sanne Traasdahl Moeller,Torben A Kruse,Uffe Birk Jensen,Joseph Vijai,Kara Sarrel,Mark E. Robson,Noah D. Kauff,Anna Marie Mulligan,Gord Glendon,Hilmi Ozcelik,Bent Ejlertsen,Finn Cilius Nielsen,Lars Jønson,Mette K. Andersen,Yuan Chun Ding,Linda Steele,Lenka Foretova,Alex Teulé,Conxi Lázaro,Joan Brunet,Miquel Angel Pujana,Phuong L. Mai,Jennifer T. Loud,Christine Walsh,Jenny Lester,Sandra Orsulic,Steven A. Narod,Josef Herzog,Sharon Sand,Silvia Tognazzo,Simona Agata,Tibor Vaszko,JoEllen Weaver,Alexandra V. Stavropoulou,Saundra S. Buys,Atocha Romero,Miguel de la Hoya,Kristiina Aittomäki,Taru A. Muranen,Mercedes Durán,Wendy K. Chung,Adriana Lasa,Cecilia M. Dorfling,Alexander Miron,Javier Benitez,Leigha Senter,Dezheng Huo,Salina B. Chan,Anna P. Sokolenko,Jocelyne Chiquette,Laima Tihomirova,Tara M. Friebel,Bjarni A. Agnarsson,Karen H. Lu,Flavio Lejbkowicz,Paul A. James,Per Hall,Alison M. Dunning,Daniel C. Tessier,Julie M. Cunningham,Susan L. Slager,Chen Wang,Steven N. Hart,Kristen N. Stevens,Jacques Simard,Tomi Pastinen,Vernon S. Pankratz,Kenneth Offit,Douglas F. Easton,Georgia Chenevix-Trench,Antonis C. Antoniou +261 more
TL;DR: It is estimated that the breast cancer lifetime risks for the5% of BRCA1 carriers at lowest risk are 28%–50% compared to 81%–100% for the 5% at highest risk, and the ovarian cancer lifetime risk is 63% or higher, based on the known cancer risk-modifying loci.