Aurore Perrot

TL;DR: This study clearly confirms the extremely poor outcome of patients displaying "double hit", but also confirms that del(17p) alone is still a very high-risk feature, confirming its value as a prognostic indicator for poor outcome.

TL;DR: Serum albumin levels appear to be an independent prognostic factor in AML and a better parameter than BMI for evaluating the nutritional status of patients at diagnosis and the association between BMI, SA, and survival is evaluated.

TL;DR: In this article, the authors used single-cell analysis to predict patient prognosis and response to treatment for multiple myeloma (MM) in the bone marrow using a combination of cytogenetics and minimal residual disease.

TL;DR: The advent of technologies detecting minimal residual disease gives the opportunity to define the quality of response to treatment with an unpreceded sensitivity and adapt treatment accordingly and even if molecular targeting is still nascent in myeloma, some molecular features are interesting to detect at relapse to determine optimal salvage treatments.

TL;DR: Il peut s’agir de maladies indolentes liees a de petits clones de plasmocytes a faible potentiel proliferatif mais qui synthetisent une immunoglobuline monoclonale potentiellement dangereuse pour certains organes.