S
Stephane Minvielle
Researcher at University of Nantes
Publications - 158
Citations - 10117
Stephane Minvielle is an academic researcher from University of Nantes. The author has contributed to research in topics: Multiple myeloma & Gene. The author has an hindex of 39, co-authored 154 publications receiving 9013 citations. Previous affiliations of Stephane Minvielle include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
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Journal ArticleDOI
Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome
Hervé Avet-Loiseau,Michel Attal,Philippe Moreau,Catherine Charbonnel,Frédéric Garban,Cyrille Hulin,Serge Leyvraz,Mauricette Michallet,Ibrahim Yakoub-Agha,Laurent Garderet,Gerald Marit,Lucienne Michaux,Laurent Voillat,Marc Renaud,Bernard Grosbois,Gaelle Guillerm,Lotfi Benboubker,Mathieu Monconduit,Catherine Thieblemont,Philippe Casassus,Denis Caillot,Anne-Marie Stoppa,Jean-Jacques Sotto,Marc Wetterwald,Charles Dumontet,Jean-Gabriel Fuzibet,Isabelle Azais,Véronique Dorvaux,Marc Zandecki,Régis Bataille,Stephane Minvielle,Jean-Luc Harousseau,Thierry Facon,Claire Mathiot +33 more
TL;DR: In myeloma, the genomic aberrations t(4;14) and del(17p), together with beta2-microglobulin level, are important independent predictors of survival and have implications for the design of risk-adapted treatment strategies.
Journal ArticleDOI
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
Niccolo Bolli,Hervé Avet-Loiseau,David C. Wedge,Peter Van Loo,Ludmil B. Alexandrov,Inigo Martincorena,Kevin J. Dawson,Francesco Iorio,Serena Nik-Zainal,Graham R. Bignell,Jonathan Hinton,Yang Li,Jose M. C. Tubio,Stuart McLaren,Sarah O' Meara,Adam Butler,Jon W. Teague,Laura Mudie,Elizabeth Anderson,Naim U. Rashid,Yu-Tzu Tai,Masood A. Shammas,Adam S. Sperling,Mariateresa Fulciniti,Paul G. Richardson,Giovanni Parmigiani,Florence Magrangeas,Stephane Minvielle,Philippe Moreau,Michel Attal,Thierry Facon,P. Andrew Futreal,Kenneth C. Anderson,Peter J. Campbell,Nikhil C. Munshi +34 more
TL;DR: The myeloma genome is heterogeneous across the cohort, and exhibits diversity in clonal admixture and in dynamics of evolution, which may impact prognostic stratification, therapeutic approaches and assessment of disease response to treatment.
Journal ArticleDOI
International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.
Rafael Fonseca,P L Bergsagel,Johannes Drach,John D. Shaughnessy,Norma C. Gutiérrez,Alexander Keith Stewart,Gareth J. Morgan,B Van Ness,Marta Chesi,Stephane Minvielle,Antonino Neri,Bart Barlogie,W. M. Kuehl,Peter Liebisch,Faith E. Davies,Selina Chen-Kiang,Brian G.M. Durie,Ruben D. Carrasco,Orhan Sezer,Tony Reiman,Linda M. Pilarski,Hervé Avet-Loiseau,Hervé Avet-Loiseau +22 more
TL;DR: In this paper, the authors proposed a framework for the classification of myeloma subtypes and provided recommendations for genetic testing, which needs to be incorporated into daily clinical practice and also as an essential component of all ongoing and future clinical trials.
Journal ArticleDOI
Genetics and Cytogenetics of Multiple Myeloma A Workshop Report
Rafael Fonseca,Bart Barlogie,Régis Bataille,Christian Bastard,P. Leif Bergsagel,Marta Chesi,Faith E. Davies,Johannes Drach,Philip R. Greipp,Ilan R. Kirsch,W. Michael Kuehl,Jesus M. Hernandez,Stephane Minvielle,Linda M. Pilarski,John D. Shaughnessy,A. Keith Stewart,Hervé Avet-Loiseau,Hervé Avet-Loiseau +17 more
TL;DR: This summary describes the consensus recommendations arising from that meeting with special emphasis on novel genetic observations and Gene expression platforms capable of detecting many of the genetic aberrations found in the clonal cells of myeloma.
SPOTLIGHT REVIEW International Myeloma Working Group molecular classification of multiple myeloma: spotlight review
R Fonseca,P L Bergsagel,Johannes Drach,John D. Shaughnessy,Norma C. Gutiérrez,Alexander Keith Stewart,G Morgan,B Van Ness,Marta Chesi,Stephane Minvielle,Antonino Neri,Bart Barlogie,W. M. Kuehl,Peter Liebisch,Faith E. Davies,Selina Chen-Kiang,Ruben D. Carrasco,Orhan Sezer,Tony Reiman,Linda M. Pilarski,Hervé Avet-Loiseau,Samuel Oschin +21 more
TL;DR: It is proposed that genetic testing needs to be incorporated into daily clinical practice and also as an essential component of all ongoing and future clinical trials.