Aviv Weinstein

TL;DR: Growing evidence suggests that behavioral addictions resemble substance addictions in many domains, including natural history, phenomenology, tolerance, comorbidity, overlapping genetic contribution, neurobiological mechanisms, and response to treatment, supporting the DSM-V Task Force proposed new category of Addiction and Related Disorders encompassing both substance use disorders and non-substance addictions.

TL;DR: Although Internet-addicted individuals have difficulty suppressing their excessive online behaviors in real life, little is known about the patho-physiological and cognitive mechanisms responsible for Internet addiction, and it is currently impossible to recommend any evidence-based treatment of Internet addiction.

TL;DR: Evidence has been obtained that activity in the orbitofrontal cortex and its connections plays a role in several components of the maladaptive behavior of substance abuse, including expectancy, craving and impaired decision making.

TL;DR: The brain imaging study showed that healthy control subjects had reduced dopamine D2 receptor occupancy after playing a motorbike riding computer game compared with baseline levels of binding consistent with increased release and binding to its receptors, supporting the notion that psycho-stimulant users have decreased sensitivity to natural reward.

TL;DR: Despite the lack of success in most studies to date, increasing efforts are being made to develop medications for the treatment of methamphetamine dependence and several promising agents are targets of further research.