Aydin Tozeren

TL;DR: It is predicted that a crossbridge head is more likely to re-attach to its previously strained position than remain unattached while the other head is attached, leading to the slow decay of force, which suggests that crossbridge stiffness is determined either by the extensibility of the double helical tail region or its junction to the thick filament backbone.

TL;DR: Results show that methods based on dichotomizing tend to have consistently poor performance while C-index, D- index, and k-means perform well in most settings, and overall, the Cox regression method had the strongest performance based on tests of accuracy, reliability, and robustness.

TL;DR: The method presented here produces predictions of protein phosphorylation events with high accuracy and mid-level coverage and can be used in expanding the currently available drafts of cell signaling pathways and thus will be an important tool in the development of combination drug therapies targeting complex diseases.

TL;DR: This study produces for the first time, a signature, in the form of a robust list of gene circuitry whose presence or absence could potentially define the pathogenicity of a microbiome, using the KEGG repository and extensive literature searches.

TL;DR: An analytical method is developed to deduce the constitutive equations of fibers embedded in a thick shell from the time-variant pressure volume curves obtained by experimental procedures, finding Arbitrary coefficients appearing in the fiber stress-equation are also present in the resultant time-Variant pressure-volume relation.