B
Baekgyu Kim
Researcher at Seoul National University
Publications - 7
Citations - 554
Baekgyu Kim is an academic researcher from Seoul National University. The author has contributed to research in topics: RNA & RNA silencing. The author has an hindex of 6, co-authored 7 publications receiving 397 citations.
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Journal ArticleDOI
LIN28A Is a Suppressor of ER-Associated Translation in Embryonic Stem Cells
Jun Cho,Hyeshik Chang,S. Chul Kwon,Baekgyu Kim,Yoosik Kim,Jun-Ho Choe,Minju Ha,Yoon Ki Kim,V. Narry Kim +8 more
TL;DR: A genome-wide view of the molecular function of LIN28A in mouse embryonic stem cells is obtained by carrying out RNA crosslinking-immunoprecipitation-sequencing (CLIP-seq) and ribosome footprinting and it is found that, in addition to let-7 precursors,LIN28A binds to a large number of spliced mRNAs.
Journal ArticleDOI
PKR Senses Nuclear and Mitochondrial Signals by Interacting with Endogenous Double-Stranded RNAs.
Yoosik Kim,Yoosik Kim,Joha Park,Sujin Kim,Min A. Kim,Myeong-Gyun Kang,Chulhwan Kwak,Minjeong Kang,Baekgyu Kim,Hyun-Woo Rhee,V. Narry Kim +10 more
TL;DR: In this paper, a formaldehyde-mediated crosslinking and immunoprecipitation sequencing was performed to find that various noncoding RNAs interact with protein kinase RNA-activated (PKR) and showed that the majority of the PKR-interacting RNA repertoire is occupied by mtRNAs.
Journal Article
PKR senses nuclear and mitochondrial signals byinteracting with endogenous double-stranded RNAs
Yoosik Kim,Joha Park,Sujin Kim,Mina Kim,Myeong-Gyun Kang,Chulhwan Kwak,Minjeong Kang,Baekgyu Kim,Hyun-Woo Rhee,V. Narry Kim +9 more
TL;DR: This work unveils dynamic regulation of PKR even without infection and establishes PKR as a sensor for nuclear and mitochondrial signaling cues in regulating cellular metabolism.
Journal ArticleDOI
Genome-wide Mapping of DROSHA Cleavage Sites on Primary MicroRNAs and Noncanonical Substrates
TL;DR: In this article, a protocol termed "formaldehyde crosslinking, immunoprecipitation, and sequencing (fCLIP-seq)" was proposed to identify DROSHA cleavage sites at single-nucleotide resolution.
Journal ArticleDOI
fCLIP-seq for transcriptomic footprinting of dsRNA-binding proteins: Lessons from DROSHA
Baekgyu Kim,V. Narry Kim +1 more
TL;DR: In this article, a formaldehyde crosslinking, immunoprecipitation and sequencing (fCLIP-seq) method was proposed to map DROSHA cleavage sites at single nucleotide resolution.