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Balaji Chandrasekaran

Researcher at University of Louisville

Publications -  32
Citations -  361

Balaji Chandrasekaran is an academic researcher from University of Louisville. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 9, co-authored 21 publications receiving 224 citations. Previous affiliations of Balaji Chandrasekaran include Annamalai University.

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Targeting aberrant expression of Notch‐1 in ALDH+ cancer stem cells in breast cancer

TL;DR: The results suggest that Notch-1 could be an attractive target and inhibition of Notch‐1 by Psoralidin may prevent pathogenesis of breast cancer as well as metastasis and inhibit the growth in ALDH+ and ALDH− tumors.
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Geraniol attenuates oxidative stress by Nrf2 activation in diet-induced experimental atherosclerosis.

TL;DR: In this article, the role of geraniol (GOH) in preserving the plasma lipid status, endothelial function, antioxidant status, and inhibition of lipid peroxidation in hamsters fed an atherogenic diet (AD) was evaluated.
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Effect of geraniol, a plant derived monoterpene on lipids and lipid metabolizing enzymes in experimental hyperlipidemic hamsters.

TL;DR: It is illustrated that GOH is effective in lowering the risk of hyperlipidemia in AD fed hamsters by inhibiting HMG CoA reductase and suppressing lipogenesis.
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Geraniol attenuates fibrosis and exerts anti-inflammatory effects on diet induced atherogenesis by NF-κB signaling pathway.

TL;DR: GOH supplementation greatly prevented the remodeling of tissues by enhancing the free radical scavenging and anti-inflammatory effects and it can be suggested that GOH (100mg/kg b.w) prevents the atherogenic diet induced fibrosis in experimental hamsters.