B
Baldur Sveinbjørnsson
Researcher at University of Tromsø
Publications - 119
Citations - 4715
Baldur Sveinbjørnsson is an academic researcher from University of Tromsø. The author has contributed to research in topics: Neuroblastoma & Receptor. The author has an hindex of 38, co-authored 116 publications receiving 4067 citations. Previous affiliations of Baldur Sveinbjørnsson include Boston Children's Hospital & Health Science University.
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Journal ArticleDOI
Infusion of methylene blue in human septic shock: a pilot, randomized, controlled study.
Mikhail Y. Kirov,Oleg V. Evgenov,Natalia V. Evgenov,Elena M. Egorina,Mikhail A. Sovershaev,Baldur Sveinbjørnsson,Eduard V. Nedashkovsky,Lars J. Bjertnaes +7 more
TL;DR: In human septic shock, continuously infused MB counteracts myocardial depression, maintains oxygen transport, and reduces concurrent adrenergic support, and Infusion of MB appears to have no significant adverse effects on the selected organ function variables.
Journal ArticleDOI
The antimicrobial peptide, lactoferricin B, is cytotoxic to neuroblastoma cells in vitro and inhibits xenograft growth in vivo
Liv Tone Eliassen,Gerd Berge,Arild Leknessund,Wikman Mari,Inger Lindin,Cecilie Løkke,Frida Ponthan,John Inge Johnsen,Baldur Sveinbjørnsson,Per Kogner,Trond Flægstad,Øystein Rekdal +11 more
TL;DR: Results revealed a selective destabilizing effect of LfcinB on two important targets in the neuroblastoma cells, the cytoplasmic‐ and the mitochondria membrane.
Journal ArticleDOI
Detection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic target
Ninib Baryawno,Afsar Rahbar,Nina Wolmer-Solberg,Chato Taher,Jenny Odeberg,Anna Darabi,Zahidul Khan,Baldur Sveinbjørnsson,Ole-Martin Fuskevåg,Lova Segerström,Magnus Nordenskjöld,Peter Siesjö,Per Kogner,John Inge Johnsen,Cecilia Söderberg-Nauclér +14 more
TL;DR: It is shown that a large proportion of primary medulloblastomas and medullOBlastoma cell lines are infected with HCMV and that COX-2 expression, along with PGE2 levels, in tumors is directly modulated by the virus.
Journal Article
Evidence for a direct antitumor mechanism of action of bovine lactoferricin.
Liv Tone Eliassen,Gerd Berge,Baldur Sveinbjørnsson,John S. Svendsen,Lars H. Vorland,Øystein Rekdal +5 more
TL;DR: It is demonstrated that LfcinB elicits an antitumor effect mediated through a direct mechanism of action not observed with LFB or LFCinM, and significantly reduced the size of solid Meth A tumors.
Journal ArticleDOI
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance.
Malin Wickström,Cecilia Dyberg,Jelena Milosevic,Christer Einvik,Raul Calero,Baldur Sveinbjørnsson,Baldur Sveinbjørnsson,Emma Sandén,Anna Darabi,Peter Siesjö,Marcel Kool,Per Kogner,Ninib Baryawno,John Inge Johnsen +13 more
TL;DR: A significant correlation between Wnt signalling and MGMT expression in cancers with different origin is shown and could have potential therapeutic implications for chemoresistant cancers, especially of brain tumours where the use of temozolomide is frequently used in treatment.