M
Magnus Nordenskjöld
Researcher at Karolinska Institutet
Publications - 300
Citations - 20169
Magnus Nordenskjöld is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Gene & Locus (genetics). The author has an hindex of 73, co-authored 293 publications receiving 18886 citations. Previous affiliations of Magnus Nordenskjöld include Stockholm County Council & Karolinska University Hospital.
Papers
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Journal ArticleDOI
The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis.
Charis Eng,Charis Eng,David Clayton,I Schuffenecker,Gilbert M. Lenoir,Gilbert J. Cote,Robert F. Gagel,Hans Kristian Ploos van Amstel,Cornelis J.M. Lips,Isamu Nishisho,Shin ichiro Takai,Deborah J. Marsh,Deborah J. Marsh,Bruce G. Robinson,Karin Frank-Raue,Friedhelm Raue,Feiyu Xue,Walter W. Noll,Cristina Romei,Furio Pacini,Monika Fink,Bruno Niederle,Jan Zedenius,Magnus Nordenskjöld,Paul Komminoth,Geoffrey N. Hendy,Hossein Gharib,Stephen N. Thibodeau,André Lacroix,Andrea Frilling,Bruce A.J. Ponder,Bruce A.J. Ponder,Lois M. Mulligan +32 more
TL;DR: It is suggested that genotype-phenotype correlations do exist and, if made reliably absolute, could prove useful in the future in clinical management with respect to screening, surveillance, and prophylaxis, as well as provide insight into the genetic effects of particular mutations.
Journal ArticleDOI
Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern.
Eva Enmark,Markku Pelto-Huikko,Markku Pelto-Huikko,Kaj Grandien,Svetlana Lagercrantz,Jacob Lagercrantz,Gabriel Fried,Magnus Nordenskjöld,Jan-Åke Gustafsson +8 more
TL;DR: Data regarding the genomic structure and chromosomal localization of the human ERβ gene is presented, demonstrating that two independent ER genes do exist in the human and that this receptor is expressed in multiple tissues.
Journal ArticleDOI
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma
TL;DR: By comparing constitutional and tumour tissue genotypes of insulinomas from a pair of brothers who had inherited MEN-1 from their mother, it is shown that oncogenesis in these cases involves unmasking of a recessive mutation at this locus.
Journal ArticleDOI
Cytogenetic analysis by chromosome painting using dop-pcr amplified flow-sorted chromosomes
Håkan Telenius,A H Pelmear,Alan Tunnacliffe,Nigel P. Carter,A. Behmel,Malcolm A. Ferguson-Smith,Magnus Nordenskjöld,Roswitha Pfragner,Bruce A.J. Ponder +8 more
TL;DR: This study shows that flow sorting of aberrant chromosomes and chromosome painting can be used as a rapid aid to cytogenetic analysis, particularly in cases of difficult karyotypes, such as tumours.
Journal Article
Clonal Genomic Alterations in Glioma Malignancy Stages
C D James,E. Carlbom,Jan P. Dumanski,Marc F. Hansen,Magnus Nordenskjöld,Vincent Peter Collins,Webster K. Cavenee +6 more
TL;DR: A close association of the loss of chromosome 10 sequences with the most malignant histological stage of glioma is demonstrated and glioblastoma is suggested to be a common phenotypic and malignancy terminus for glial tumors of various cellular subtypes which is reached through a common molecular pathway.