B
Bao-Sai Lu
Researcher at Hebei Medical University
Publications - 11
Citations - 100
Bao-Sai Lu is an academic researcher from Hebei Medical University. The author has contributed to research in topics: Cell growth & Chemistry. The author has an hindex of 5, co-authored 8 publications receiving 44 citations.
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Journal ArticleDOI
miR-20b-5p, TGFBR2, and E2F1 Form a Regulatory Loop to Participate in Epithelial to Mesenchymal Transition in Prostate Cancer.
Jin-Chun Qi,Zhan Yang,Yan-Ping Zhang,Bao-Sai Lu,Yue-Wei Yin,Kai-Long Liu,Wen-yong Xue,Chang-Bao Qu,Wei Li +8 more
TL;DR: A novel regulatory mechanism underlying the miR-20b-5p/TGFBR2/E2F1 axis is involved in TGF-β1-induced EMT of PCa cells, and miR+5p may be a potential therapeutic target for PCa.
Journal ArticleDOI
Down-regulated RBM5 inhibits bladder cancer cell apoptosis by initiating an miR-432-5p/β-catenin feedback loop
Yan-Ping Zhang,Kai-Long Liu,Yaxuan Wang,Zhan Yang,Zhenwei Han,Bao-Sai Lu,Jin-Chun Qi,Yue-Wei Yin,Zhihai Teng,Xueliang Chang,Jingdong Li,Hong Xin,Wei Li +12 more
TL;DR: Evidence is provided that the regulatory feedback loop among RBM5, miR‐432‐5p, and Wnt–²‐catenin is responsible for the progress of bladder cancer cells, and this study found that R BM5 expression was significantly down‐regulated in BUC tissues when compared with the adjacent nontumor tissues.
Journal ArticleDOI
The involvement of FBP1 in prostate cancer cell epithelial mesenchymal transition, invasion and metastasis by regulating the MAPK signaling pathway
Yan-Ping Zhang,Kai-Long Liu,Zhan Yang,Bao-Sai Lu,Jin-Chun Qi,Zhenwei Han,Yue-Wei Yin,Ming Zhang,De-Min Chen,Xiao-Wei Wang,Wei Li,Hong Xin +11 more
TL;DR: Evidence has been provided in this study that FBP1 gene silencing activates the MAPK pathway, which ultimately promotes cell EMT, invasion and metastasis in PCa.
Journal ArticleDOI
RBM24 exacerbates bladder cancer progression by forming a Runx1t1/TCF4/miR-625-5p feedback loop.
Yue-Wei Yin,Kai-Long Liu,Bao-Sai Lu,Wei Li,Ya-Lin Niu,Chen-Ming Zhao,Zhan Yang,Ping-Ying Guo,Jin-Chun Qi +8 more
TL;DR: In this article, the authors found that a higher level of RBM24 was correlated with poor prognosis in bladder cancer patients, and that RBM 24 positively regulated Runx1t1 expression in BC cells by binding to and enhancing Runx 1t1 mRNA stability.
Journal ArticleDOI
Upregulation of NPL4 promotes bladder cancer cell proliferation by inhibiting DXO destabilization of cyclin D1 mRNA
TL;DR: The NPL4/DXO/cyclin D1 axis exert crucial role in BC cell growth and is associated with prognosis and may represent a potential therapeutic target for BC.