Jin-Chun Qi

TL;DR: In this paper, a CRISPR-Cas9-based complex was used to activate endogenous CDK13 and circCDK13 expression in human PCa tissues and different cell lines were determined by quantitative real-time PCR and Western blot analysis.

TL;DR: A novel regulatory mechanism underlying the miR-20b-5p/TGFBR2/E2F1 axis is involved in TGF-β1-induced EMT of PCa cells, and miR+5p may be a potential therapeutic target for PCa.

TL;DR: Evidence is provided that the regulatory feedback loop among RBM5, miR‐432‐5p, and Wnt–²‐catenin is responsible for the progress of bladder cancer cells, and this study found that R BM5 expression was significantly down‐regulated in BUC tissues when compared with the adjacent nontumor tissues.

TL;DR: Evidence has been provided in this study that FBP1 gene silencing activates the MAPK pathway, which ultimately promotes cell EMT, invasion and metastasis in PCa.

TL;DR: In this article, the authors found that a higher level of RBM24 was correlated with poor prognosis in bladder cancer patients, and that RBM 24 positively regulated Runx1t1 expression in BC cells by binding to and enhancing Runx 1t1 mRNA stability.