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Barbara D. Abbott

Researcher at Research Triangle Park

Publications -  79
Citations -  6142

Barbara D. Abbott is an academic researcher from Research Triangle Park. The author has contributed to research in topics: Developmental toxicity & Receptor. The author has an hindex of 40, co-authored 79 publications receiving 5600 citations. Previous affiliations of Barbara D. Abbott include United States Environmental Protection Agency.

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AH receptor, ARNT, glucocorticoid receptor, EGF receptor, EGF, TGFα, TGFβ1, TGFβ2, and TGFβ3 expression in human embryonic palate, and effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)†

Barbara D. Abbott, +3 more
- 01 Aug 1998 - 
TL;DR: Comparison between mouse and human palates revealed interspecies variation that may be a factor in each species' response to TCDD, as well as other teratogenic exposures.
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Transcriptional ontogeny of the developing liver

Janice S. Lee, +8 more
- 19 Jan 2012 - 
TL;DR: Findings reveal the complexity of gene expression changes during liver development and maturation, and provide a foundation to predict responses to chemical and drug exposure as a function of early life-stages.
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Teratogenicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) in Mice Lacking the Expression of EGF and/or TGF-α

P. Lamont Bryant, +4 more
- 01 Jul 2001 - 
TL;DR: It is demonstrated that expression of EGF influences the induction of cleft palate by TCDD, which did not affect maternal weight gain, fetal weight, or survival, but maternal and fetal liver weights and liver-to-body weight ratios were increased in all genotypes.
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Effects of TCDD on Ah receptor, ARNT, EGF, and TGF-α expression in embryonic mouse urinary tract

Paul LaMont Bryant, +4 more
- 01 May 1997 - 
TL;DR: The epithelial cells of the embryonic mouse urinary tract expressed AhR, ARNT, EGF, and TGF-α in developmentally dependent patterns, which are involved in the regulation of embryonic cell proliferation during normal urinary tract development and are probably involvement in the hyperplastic response to TCDD.
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Embryonic palatal responses to teratogens in serum-free organ culture.

Barbara D. Abbott, +1 more
- 01 Apr 1992 - 
TL;DR: It is demonstrated that serum-free organ culture supports development of mouse, rat, and human palatal explants and the increased responsiveness to DEX or TCDD in the presence of serum suggests that an unknown factor in serum may be required for full activity.