B
Barbara E. Murray
Researcher at University of Texas at Austin
Publications - 235
Citations - 23158
Barbara E. Murray is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Enterococcus faecalis & Enterococcus faecium. The author has an hindex of 73, co-authored 232 publications receiving 21704 citations. Previous affiliations of Barbara E. Murray include Emerging Pathogens Institute & University of Texas Health Science Center at Houston.
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Enterococci from Bangkok, Thailand, with high-level resistance to currently available aminoglycosides.
TL;DR: One strain, chosen for further study, was resistant to synergism between penicillin and gentamicin, tobramycin, kanamycin, streptomycin, and amikacin and demonstrated the following enzymatic activities: 3'- and 2"-aminoglycoside phosphotransferases, 6'-aminogly coside acetyltransferase, and adenylylation of strePTomycin.
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Generation of auxotrophic mutants of Enterococcus faecalis.
TL;DR: A new methodology for constructing defined knockout mutations in E. faecalis pyrimidine biosynthetic genes in this clone (designated pKV48) is demonstrated, and computer analyses found these to be similar to genes from Bacillus subtilis and Bacillus caldolyticus pyridine biosynthesis operons.
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EbpR Is Important for Biofilm Formation by Activating Expression of the Endocarditis and Biofilm-Associated Pilus Operon (ebpABC) of Enterococcus faecalis OG1RF
Agathe Bourgogne,Kavindra V. Singh,Kristina A. Fox,Kathryn J. Pflughoeft,Barbara E. Murray,Barbara E. Murray,Danielle A. Garsin,Danielle A. Garsin +7 more
TL;DR: An ebpR deletion (DeltaebpR) mutant was found to have reduced ebpABC expression with loss of pilus production and a defect in primary adherence with, as a consequence, reduced biofilm formation.
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Contribution of the enterococcal surface protein Esp to pathogenesis of Enterococcus faecium endocarditis
Esther Heikens,Kavindra V. Singh,Karen D. Jacques-Palaz,Miranda van Luit-Asbroek,Evelien A. N. Oostdijk,Marc J. M. Bonten,Barbara E. Murray,Rob J. L. Willems +7 more
TL;DR: Esp contributes to colonization of E. faecium at the heart valves and systemic infection elicits an Esp-specific antibody response in humans, which contributes to biofilm formation.
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Quantitative analysis and partial characterization of cytotoxin production by Salmonella strains.
TL;DR: The findings indicate that salmonellae produce cytotoxin(s) that may play a role in the manifestations of the various species.