B
Barry A. Bunin
Researcher at Collaborative Drug Discovery
Publications - 46
Citations - 2140
Barry A. Bunin is an academic researcher from Collaborative Drug Discovery. The author has contributed to research in topics: Solid-phase synthesis & Cheminformatics. The author has an hindex of 21, co-authored 46 publications receiving 2078 citations. Previous affiliations of Barry A. Bunin include University of California, Berkeley.
Papers
More filters
Journal ArticleDOI
A general and expedient method for the solid-phase synthesis of 1,4-benzodiazepine derivatives
Journal ArticleDOI
The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library
TL;DR: A library of 192 structurally diverse 1,4-benzodiazepine derivatives containing a variety of chemical functionalities including amides, carboxylic acids, amines, phenols, and indoles was constructed from three components, 2-aminobenzophenones, amino acids, and alkylating agents, by employing Geysen's pin apparatus.
Book
The Combinatorial Index
TL;DR: A summary of functional group transformations for Combinatorial solid phase synthesis can be found in this paper, along with a list of abbreviations and a discussion of analytical methods for synthesizing Oligosaccharides.
Journal ArticleDOI
Novel web-based tools combining chemistry informatics, biology and social networks for drug discovery.
TL;DR: This work argues that a community-based platform that combines traditional drug discovery informatics with Web2.0 features in secure groups is believed to be the key to facilitating richer, instantaneous collaborations involving sensitive drug discovery data and intellectual property.
Patent
Compounds For Enzyme Inhibition
Mark S. Smyth,Guy J. Laidig,Ronald T. Borchardt,Barry A. Bunin,Craig M. Crews,John H. Musser,Kevin D. Shenk,Peggy A. Radel +7 more
TL;DR: In this paper, the peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases.