B
Barth-Jan van Rossum
Researcher at Leibniz Institute for Neurobiology
Publications - 41
Citations - 2150
Barth-Jan van Rossum is an academic researcher from Leibniz Institute for Neurobiology. The author has contributed to research in topics: Nuclear magnetic resonance spectroscopy & Magic angle spinning. The author has an hindex of 23, co-authored 41 publications receiving 1919 citations. Previous affiliations of Barth-Jan van Rossum include Leibniz Association.
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Journal ArticleDOI
Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers
Stefan Jehle,Ponni Rajagopal,Benjamin Bardiaux,Stefan Markovic,Stefan Markovic,Ronald Kühne,Joseph R. Stout,Victoria A. Higman,Rachel E. Klevit,Barth-Jan van Rossum,Hartmut Oschkinat,Hartmut Oschkinat +11 more
TL;DR: A pH-dependent modulation of the interaction of the IXI motif with β4 and β8 is observed, consistent with a pH- dependent regulation of the chaperone function.
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Dynamic nuclear polarization of deuterated proteins.
Ümit Akbey,W. Trent Franks,Arne H. Linden,Sascha Lange,Robert G. Griffin,Barth-Jan van Rossum,Hartmut Oschkinat +6 more
TL;DR: Making remarkable progress towards this goal has been achieved by incorporating high-frequency dynamic nuclear polarization (DNP) into the MAS NMR technique, which exploits the microwave-driven transfer of polarization from a paramagnetic center, such as nitroxide free radical, to the nuclear spins.
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Membrane-protein structure determination by solid-state NMR spectroscopy of microcrystals.
Shakeel A. Shahid,Shakeel A. Shahid,Benjamin Bardiaux,W. Trent Franks,Ludwig Krabben,Ludwig Krabben,Michael Habeck,Barth-Jan van Rossum,Dirk Linke +8 more
TL;DR: This work presents the solid-state NMR structure of the transmembrane domain of the Yersinia enterocolitica adhesin A (YadA), and acquires information on the flexibility and mobility of parts of the structure, which presents new insights into the autotransport mechanism of YadA.
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A software framework for analysing solid-state MAS NMR data
Tim J. Stevens,Rasmus H. Fogh,Wayne Boucher,Victoria A. Higman,Frank Eisenmenger,Benjamin Bardiaux,Barth-Jan van Rossum,Hartmut Oschkinat,Ernest D. Laue +8 more
TL;DR: In this paper, the CCPN analysis software package is updated and extended for solid-state magic-angle-spinning (MAS) NMR data analysis, which enables easier identification of spinning side bands, straightforward analysis of double quantum spectra, automatic consideration of non-uniform labelling schemes, as well as extension of other existing features to the needs of solidstate MAS data.
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Optimum levels of exchangeable protons in perdeuterated proteins for proton detection in MAS solid-state NMR spectroscopy
Ümit Akbey,Sascha Lange,W. Trent Franks,Rasmus Linser,Kristina Rehbein,Anne Diehl,Barth-Jan van Rossum,Bernd Reif,Hartmut Oschkinat +8 more
TL;DR: It is found that CP is more favorable compared to INEPT based transfer when the number of possible 1H,1H interactions increases, and at low levels of deuteration, resonances from rigid residues are broadened beyond detection.