Basavaraj Girennavar

TL;DR: The data obtained using in vitro models clearly establish the antioxidant potential of citrus fruit extracts, however, comprehensive studies need to be conducted to ascertain the in vivo bioavailability, safety and efficacy of such extracts in experimental animals.

TL;DR: Grapefruit juice and furocoumarins could serve as a source to develop bacterial intervention strategies targeting microbial cell signaling processes, and inhibit biofilm formation by Escherichia coli O157:H7, Salmonella typhimurium and Pseudomonas aeruginosa.

TL;DR: An efficient technique has been developed for isolation and purification of three furocoumarins that showed a substantial inhibitory effect on CYP 3A4 below 10 microM and inhibitory effects on CYB 1B1 exhibited a greater variation due to the specificity of substrates.

TL;DR: In this paper, the antioxidant capacity of pummelo and navel oranges was measured by five widely used antioxidant methods, including α,α-diphenyl-β-picrylhydrazyl (DPPH), 2,2′-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical assay and ORAC methods.

TL;DR: Grapefruit and pummelo juices were found to be potent inhibitors of cytochrome CYP3A4 and CYP2C9 isoenzymes at 25% concentration, while CyP2D6 is inhibited significantly low at all the tested concentration of juices.