B
Basil Rigas
Researcher at Stony Brook University
Publications - 144
Citations - 5751
Basil Rigas is an academic researcher from Stony Brook University. The author has contributed to research in topics: Cancer & Apoptosis. The author has an hindex of 43, co-authored 143 publications receiving 5396 citations. Previous affiliations of Basil Rigas include State University of New York System & Cornell University.
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Infrared spectroscopy of exfoliated human cervical cells: evidence of extensive structural changes during carcinogenesis.
TL;DR: Infrared spectra obtained from exfoliated cervical cells from 156 females revealed that in the malignant cervical tissue there were extensive changes in the degree of hydrogen bonding of phosphodiester groups of nucleic acids and C--OH groups of proteins, as well as changes inThe degree of disorder of methylene chains of lipids.
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Nonsteroidal anti-inflammatory drugs and colorectal cancer: evolving concepts of their chemopreventive actions.
Steven J. Shiff,Basil Rigas +1 more
TL;DR: The Evidence That NSAIDs are antineoplastic, prominently in the colon, is derived from three lines of evidence: animal studies, clinical studies and case reports, and epidemiological data.
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Cytologically normal cells from neoplastic cervical samples display extensive structural abnormalities on IR spectroscopy: Implications for tumor biology
Menashi A. Cohenford,Basil Rigas +1 more
TL;DR: The findings suggest that (i) the structural changes underlying the spectroscopic changes are involved in or are a product of cervical carcinogenesis and (ii) the neoplastic process may be more extensive than currently recognized with morphological criteria.
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Potentiometric sensors based on surface molecular imprinting: Detection of cancer biomarkers and viruses
Yantian Wang,Zhiquan Zhang,Vijay Jain,Jinju Yi,Steffen Mueller,Jonathan Sokolov,Zhenxian Liu,Kalle Levon,Basil Rigas,Miriam Rafailovich +9 more
TL;DR: The application of the principles of molecular imprinting to the development of a new method for the detection of protein cancer biomarkers and to protein-based macromolecular structures such as the capsid of a virion is demonstrated.
Journal Article
Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs: implications for colon cancer chemoprevention.
TL;DR: Three NO-NSAIDs reduced the growth of cultured HT-29 colon adenocarcinoma cells much more effectively than the corresponding NSAIDs, which makes them promising candidates for chemopreventive agents against colon cancer.