Batu K. Sharma-Kuinkel

TL;DR: An overview of basic and clinical MRSA research is provided and the expansive body of literature on the epidemiology, transmission, genetic diversity, evolution, surveillance and treatment of MRSA is explored.

TL;DR: Findings suggest that two genes, Tnfaip8 and Seh1l, may contribute to susceptibility to S. aureus in A/J mice, and represent promising candidates for human genetic susceptibility studies.

TL;DR: Systematic approaches for monitoring complications of SAB and genotyping the corresponding bloodstream isolates will help identify the emergence of hypervirulent clones and likely improve clinical management of this syndrome.

TL;DR: The case of a 60-year-old man with septic shock that was diagnosed in 24 hours by a novel whole-genome next-generation sequencing assay shows great promise in identifying fastidious pathogens, and, if validated, it has profound implications for infectious disease diagnosis.

TL;DR: Compared to prototypical S. aureus strains, S. argenteus was more susceptible to oxidative stress and neutrophil killing in vitro and had reduced virulence in murine sepsis and skin infection models, which is due to mechanisms unrelated to lack of staphyloxanthin production.