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Beatrice Mandon-Pepin
Researcher at Université Paris-Saclay
Publications - 43
Citations - 1388
Beatrice Mandon-Pepin is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Gene & Meiosis. The author has an hindex of 18, co-authored 37 publications receiving 1144 citations. Previous affiliations of Beatrice Mandon-Pepin include Institut national de la recherche agronomique & École nationale vétérinaire d'Alfort.
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FOXL2 activates P450 aromatase gene transcription: towards a better characterization of the early steps of mammalian ovarian development.
Maëlle Pannetier,Stéphane Fabre,Frank Batista,Ayhan Kocer,Lauriane Renault,Geneviève Jolivet,Beatrice Mandon-Pepin,Corinne Cotinot,Reiner A. Veitia,Eric Pailhoux +9 more
TL;DR: A better characterization of early ovarian development in goat is provided, and experimental evidence demonstrating that FOXL2 represents a direct transcriptional activator of the CYP19 gene through its ovarian-specific promoter 2 is provided.
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Exposure to a complex cocktail of environmental endocrine-disrupting compounds disturbs the Kisspeptin/GPR54 system in ovine hypothalamus and pituitary gland
Michelle Bellingham,Paul Fowler,Maria R. Amezaga,Stewart M. Rhind,Corrine Cotinot,Beatrice Mandon-Pepin,Richard M. Sharpe,Neil P. Evans +7 more
TL;DR: This study demonstrates that the developing fetus is sensitive to real-world mixtures of environmental chemicals, which cause significant neuroendocrine alterations, and represents a novel, additional pathway through which environmental chemicals perturb human reproduction.
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Genetic investigation of four meiotic genes in women with premature ovarian failure.
Beatrice Mandon-Pepin,Philippe Touraine,Frédérique Kuttenn,Céline Derbois,A. Rouxel,Fumihiko Matsuda,Alain Nicolas,Corinne Cotinot,Marc Fellous +8 more
TL;DR: The symptoms of infertility observed in the DMC1 homozygote mutation carrier and in both patients with a heterozygous substitution in exon 2 of the MSH5 gene provide indirect evidence of the role of genes involved in meiotic recombination in the regulation of ovarian function.
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An overview of gene expression dynamics during early ovarian folliculogenesis: specificity of follicular compartments and bi-directional dialog
Agnès Bonnet,Cédric Cabau,Olivier Bouchez,Julien Sarry,Nathalie Marsaud,Sylvain Foissac,Florent Woloszyn,Philippe Mulsant,Beatrice Mandon-Pepin +8 more
TL;DR: This is the first comprehensive exploration of transcriptomes derived from in vivo oocytes and GCs at key stages in early follicular development in sheep and will be a valuable resource for unraveling human ovarian dysfunction such as premature ovarian failure (POF).
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Expression Profiles and Chromosomal Localization of Genes Controlling Meiosis and Follicular Development in the Sheep Ovary
Beatrice Mandon-Pepin,Anne Oustry-Vaiman,Bernard Vigier,François Piumi,Edmond P. Cribiu,Corinne Cotinot +5 more
TL;DR: The RT-PCR analysis revealed that the two germline-specific genes, DAZL and Boule, were expressed between 49 and 94 days postcoitum with a similar pattern to typical meiosis genes, suggesting their possible participation in prophase of meiosis I.