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Béatrice Riteau
Researcher at French Alternative Energies and Atomic Energy Commission
Publications - 16
Citations - 2088
Béatrice Riteau is an academic researcher from French Alternative Energies and Atomic Energy Commission. The author has contributed to research in topics: HLA-G & Human leukocyte antigen. The author has an hindex of 13, co-authored 16 publications receiving 2016 citations.
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Journal ArticleDOI
HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance
Pascale Paul,Nathalie Rouas-Freiss,Iman Khalil-Daher,Philippe Moreau,Béatrice Riteau,F A Le Gal,Marie-Françoise Avril,Jean Dausset,Jean-Gérard Guillet,Edgardo D. Carosella +9 more
TL;DR: It appears of critical importance to consider the specific role of HLA-G expression in tumors in the design of future cancer immunotherapies.
Journal ArticleDOI
HLA-G2, -G3, and -G4 Isoforms Expressed as Nonmature Cell Surface Glycoproteins Inhibit NK and Antigen-Specific CTL Cytolysis
Béatrice Riteau,Nathalie Rouas-Freiss,Catherine Menier,Pascale Paul,Jean Dausset,Edgardo D. Carosella +5 more
TL;DR: Evidence is provided here that HLA-G2, -G3, and -G4 truncated isoforms reach the cell surface of transfected cells, as endoglycosidase H-sensitive glycoproteins, after a 2-h chase period, which highlights the immunomodulatory role that HLA-G1 expression is altered.
Journal ArticleDOI
HLA-G-mediated inhibition of antigen-specific cytotoxic T lymphocytes.
Frédérique-Anne Le Gal,Béatrice Riteau,Christine Sedlik,Iman Khalil-Daher,Catherine Menier,Jean Dausset,Jean-Gérard Guillet,Edgardo D. Carosella,Nathalie Rouas-Freiss +8 more
TL;DR: It is demonstrated that the non-classical MHC class I molecule HLA-G impairs specific cytolytic T cell functions in addition to its well-established inhibition of NK lysis, appearing to have an extensive role in immune tolerance.
Journal ArticleDOI
HLA-G inhibits the allogeneic proliferative response
Béatrice Riteau,Catherine Menier,Iman Khalil-Daher,Christine Sedlik,Jean Dausset,Nathalie Rouas-Freiss,Edgardo D. Carosella +6 more
TL;DR: It is shown that HLA-G is able to inhibit T cell allo-proliferation and this findings provide new insight into the role of Hla-G in preventing allograft rejection.
Journal ArticleDOI
HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition
Béatrice Riteau,Catherine Menier,Iman Khalil-Daher,Silvia Martinozzi,Marika Pla,Jean Dausset,Edgardo D. Carosella,Nathalie Rouas-Freiss +7 more
TL;DR: Results demonstrate that in the absence of HLA-G1, the naturally expressed HLA class I-mediated NK inhibition is predominantly exerted by Hla-E through binding with CD94/NKG2A, and once HLA -G1 is expressed, it becomes the major NK inhibitory ligand.