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Bee K. Tan
Researcher at University of Leicester
Publications - 113
Citations - 6638
Bee K. Tan is an academic researcher from University of Leicester. The author has contributed to research in topics: Adipokine & Insulin resistance. The author has an hindex of 43, co-authored 104 publications receiving 5312 citations. Previous affiliations of Bee K. Tan include National Health Service & University Hospitals Coventry and Warwickshire NHS Trust.
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Journal ArticleDOI
Progression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis
Elpida Vounzoulaki,Kamlesh Khunti,Kamlesh Khunti,Sophia C. Abner,Sophia C. Abner,Bee K. Tan,Melanie J. Davies,Clare L Gillies,Clare L Gillies +8 more
TL;DR: Women with a history of GDM appear to have a nearly 10-fold higher risk of developing type 2 diabetes mellitus than those with a normoglycaemic pregnancy, particularly in the early years after pregnancy.
Journal ArticleDOI
Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis
TL;DR: The data provide the first evidence of visfatin-induced endothelial VEGF and MMP production and activity and show for the first time the involvement of the MAPK and PI3K/Akt signalling pathways in mediating these actions, as well as endothelial cell proliferation.
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Identification of chemerin receptor (ChemR23) in human endothelial cells: chemerin-induced endothelial angiogenesis.
TL;DR: The novel presence of ChemR23 in human ECs and its significant up-regulation by pro-inflammatory cytokines, TNF-alpha, IL-1beta and IL-6 are demonstrated and data provide the first evidence of chemerin-induced endothelial angiogenesis and MMP production and activity.
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Identification of nesfatin-1 in human and murine adipose tissue: a novel depot-specific adipokine with increased levels in obesity.
Manjunath Ramanjaneya,Jing Chen,James Brown,Gyanendra Tripathi,Manfred Hallschmid,Suketu Patel,Werner Kern,Edward W. Hillhouse,Hendrik Lehnert,Hendrik Lehnert,Bee K. Tan,Harpal S. Randeva +11 more
TL;DR: It is reported that nesfatin-1 is a novel depot specific adipokine preferentially produced by sc tissue, with obesity- and food deprivation-regulated expression.
Journal ArticleDOI
Omentin-1, a novel adipokine, is decreased in overweight insulin-resistant women with polycystic ovary syndrome: ex vivo and in vivo regulation of omentin-1 by insulin and glucose.
Bee K. Tan,Raghu Adya,S Farhatullah,Kris C. Lewandowski,Kris C. Lewandowski,J. Paul O'Hare,Hendrik Lehnert,Hendrik Lehnert,Harpal S. Randeva +8 more
TL;DR: Novel findings reveal that omentin-1 is downregulated by insulin and glucose, which may, in part, explain the decreased oment in-1 levels observed in overweight women with PCOS.