B
Belén Salinas
Researcher at University of Carabobo
Publications - 22
Citations - 2499
Belén Salinas is an academic researcher from University of Carabobo. The author has contributed to research in topics: Rotavirus & Rotavirus vaccine. The author has an hindex of 11, co-authored 22 publications receiving 2441 citations.
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Journal ArticleDOI
Safety and Efficacy of an Attenuated Vaccine against Severe Rotavirus Gastroenteritis
Guillermo M. Ruiz-Palacios,Irene Pérez-Schael,F. Raúl Velázquez,Hector Abate,Thomas Breuer,Sue Ann Costa Clemens,Brigitte Cheuvart,Felix Espinoza,Paul Gillard,Bruce L. Innis,Yolanda Cervantes,Alexandre da Costa Linhares,Pio Lopez,Mercedes Macias-Parra,Eduardo Ortega-Barria,Vesta Richardson,Doris Maribel Rivera-Medina,Luis Rivera,Belén Salinas,Noris Pavía-Ruz,Jorge Salmerón,Ricardo Rüttimann,Juan Carlos Tinoco,Pilar Rubio,Ernesto Nuñez,M. Lourdes Guerrero,Juan Pablo Yarzabal,Silvia Damaso,Nadia Tornieporth,Xavier Sáez-Llorens,Rodrigo Vergara,Timo Vesikari,Alain Bouckenooghe,Ralf Clemens,Beatrice De Vos,Miguel O'Ryan +35 more
TL;DR: Two oral doses of the live attenuated G1P[8] HRV vaccine were highly efficacious in protecting infants against severe rotavirus gastroenteritis, significantly reduced the rate of severe gastroenteropathy from any cause, and were not associated with an increased risk of intussusception.
Journal ArticleDOI
Evaluation of safety, immunogenicity and efficacy of an attenuated rotavirus vaccine, RIX4414: A randomized, placebo-controlled trial in Latin American infants.
Belén Salinas,Irene Pérez Schael,Alexandre da Costa Linhares,Guillermo M Ruiz Palacios,M. Lourdes Guerrero,Juan Pablo Yarzabal,Yolanda Cervantes,SueAnn Costa Clemens,Silvia Damaso,Karin Hardt,Beatrice De Vos +10 more
TL;DR: Two doses of RIX4414 are highly efficacious, providing cross-protection against any and severe rotavirus gastroenteritis and hospitalization to infants in Latin America and proof of concept that the monovalent G1P1A P[8] human rotav virus vaccine elicits cross- protection against the G9 strain.
Journal ArticleDOI
A rotavirus vaccine for prophylaxis of infants against rotavirus gastroenteritis.
Beatrice De Vos,Timo Vesikari,Alexandre da Costa Linhares,Belén Salinas,Irene Pérez-Schael,Guillermo M. Ruiz-Palacios,Maria de Lourdes Guerrero,Kong Boo Phua,Andrée Delem,Karin Hardt +9 more
TL;DR: Results show prospects for widespread use of Rotarix to reduce rotavirus disease burden and warrant continued worldwide evaluation.
Journal ArticleDOI
Rotavirus-associated medical visits and hospitalizations in South America: a prospective study at three large sentinel hospitals.
Miguel O'Ryan,Irene Pérez-Schael,Nora Mamani,Alfredo Peña,Belén Salinas,Germán González,Fernanda Gonzalez,David O. Matson,Jorge Gomez +8 more
TL;DR: It is estimated that ∼106 000/21 000, 48 000/8000 and 98 000/31 000 rotavirus-associated medical visits/hospitalizations occur yearly in Argentina, Chile and Venezuela, respectively.
Journal ArticleDOI
Efficacy of the human rotavirus vaccine RIX4414 in malnourished children
Irene Pérez-Schael,Belén Salinas,María Tomat,Alexandre da Costa Linhares,M. Lourdes Guerrero,Guillermo M. Ruiz-Palacios,Alain Bouckenooghe,Juan Pablo Yarzabal +7 more
TL;DR: RIX4414 significantly decreased the rate of RVGE regardless of nutritional status, which suggests that this patient group can also benefit from rotavirus vaccination.