B
Benoit Vallet
Researcher at university of lille
Publications - 192
Citations - 9098
Benoit Vallet is an academic researcher from university of lille. The author has contributed to research in topics: Septic shock & Intensive care. The author has an hindex of 48, co-authored 192 publications receiving 8281 citations. Previous affiliations of Benoit Vallet include University of Alabama at Birmingham.
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Journal ArticleDOI
Myofilament calcium sensitivity is decreased in skinned cardiac fibres of endotoxin-treated rabbits
TL;DR: Myofilament Ca2+ sensitivity is decreased in skinned fibres taken from rabbit myocardium after i.v. endotoxin injection, and this effect is dose- and time-dependent, and reversible with time.
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Preconditioning by an in situ administration of hydrogen peroxide : Involvement of reactive oxygen species and mitochondrial ATP-dependent potassium channel in a cerebral ischemia-reperfusion model
Malika Simerabet,Emmanuel Robin,Ines Aristi,Sebastien Adamczyk,Benoît Tavernier,Benoit Vallet,Régis Bordet,Gilles Lebuffe +7 more
TL;DR: This study evaluated ROS involvement during the initial phase of delayed preconditioning and its relationship with mitoK(+)(-ATP) opening in a rat model of cerebral ischemia-reperfusion to clarify the strong relationship between ROS and mito(+)O(2), which needs to be clarified.
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Role of the vascular endothelium in O2 extraction during progressive ischemia in canine skeletal muscle
S. E. Curtis,Benoit Vallet,Mark J. Winn,J. B. Caufield,C. E. King,C. K. Chapler,Stephen M. Cain +6 more
TL;DR: The data suggest that products of the vascular endothelium play an important role in the matching of O2 supply to demand during supply limitation in skeletal muscle.
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Sources of variability on the estimate of treatment effect in the PROWESS trial: implications for the design and conduct of future studies in severe sepsis.
William L. Macias,Benoit Vallet,Gordon R. Bernard,Jean Louis Vincent,Pierre-François Laterre,David R. Nelson,P Alexander Derchak,Jean-François Dhainaut +7 more
TL;DR: A learning curve appeared to be present within the PROWESS trial such that the ability to demonstrate efficacy improved with increasing site experience and this potential learning curve may have implications for design of future trials.
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Survey of the use of catecholamines by French physicians
TL;DR: A lack of standardization appears in the use of catecholamines by French physicians, particularly for improvement of regional circulation and management of high-risk surgical patients, and Guidelines that define the place of each catechlamine in these settings are required to improve the quality of prescription.