B
Bernard Lammek
Researcher at University of Gdańsk
Publications - 109
Citations - 1699
Bernard Lammek is an academic researcher from University of Gdańsk. The author has contributed to research in topics: Vasopressin & Arginine. The author has an hindex of 20, co-authored 109 publications receiving 1652 citations. Previous affiliations of Bernard Lammek include Martin Luther University of Halle-Wittenberg & Academy of Sciences of the Czech Republic.
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[1-(.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid),2-(O-methyl)tyrosine]arginine-vasopressin and [1-(.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid)]arginine-vasopressin, two highly potent antagonists of the vasopressor response to arginine-vasopressin
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Solid-phase synthesis of 16 potent (selective and nonselective) in vivo antagonists of oxytocin.
Maurice Manning,Marian Kruszynski,Krzysztof Bańkowski,Aleksandra Olma,Bernard Lammek,Ling Ling Cheng,Wieslaw A. Klis,Janny Seto,Jaya Haldar,Wilbur H. Sawyer +9 more
TL;DR: The synthesis and some pharmacological properties of 16 new in vivo antagonists of oxytocin are described, based on modifications of three peptides: A, B, and C.
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Synthetic antagonists of in vivo antidiuretic and vasopressor responses to arginine-vasopressin.
TL;DR: Findings indicate O-ethyl substitution on the tyrosine at position 2 is optimal for antiantidiuretic potency and that L-arginine is far superior to D- arginine in this regard also.
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Raman and surface-enhanced Raman spectroscopy investigation of vasopressin analogues containing 1-aminocyclohexane-1-carboxylic acid residue.
TL;DR: The results suggest that [corrected] the binding of the Tyr-ionized phenolic group might be responsible for the selectivity of the analogues of AVP and its [Cpa1, Acc3]AVP analogues.
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The Multi-Leu Peptide Inhibitor Discriminates Between PACE4 and Furin And Exhibits Antiproliferative Effects On Prostate Cancer Cells
Christine Levesque,Martin Fugère,Anna Kwiatkowska,Frédéric Couture,Roxane Desjardins,Sophie Routhier,Philippe Moussette,Adam Prahl,Bernard Lammek,Jon R. Appel,Richard A. Houghten,François D'Anjou,Yves L. Dory,Witold Neugebauer,Robert Day +14 more
TL;DR: It is concluded that peptide-based inhibitors can yield specific PC inhibitors and that the ML-peptide is an important lead compound that could potentially have applications in prostate cancer.