B
Bertrand Knebelmann
Researcher at Necker-Enfants Malades Hospital
Publications - 155
Citations - 11251
Bertrand Knebelmann is an academic researcher from Necker-Enfants Malades Hospital. The author has contributed to research in topics: Kidney disease & Alport syndrome. The author has an hindex of 48, co-authored 133 publications receiving 8870 citations. Previous affiliations of Bertrand Knebelmann include Beth Israel Deaconess Medical Center & University of Paris.
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Journal ArticleDOI
Case report and literature review: Glomerular and neurologic thrombotic microangiopathy as a primary manifestation of multicentric castleman disease.
Adrien Flahault,Marguerite Vignon,Marion Rabant,Aurélie Hummel,Laure-Hélène Noël,Danielle Canioni,Bertrand Knebelmann,Felipe Suarez,Khalil El Karoui +8 more
TL;DR: Although rare, this diagnosis is worth knowing, as specific treatment has to be started as soon as possible and proved to be efficient in this case as well as in other reports in the literature.
Journal ArticleDOI
Endostatin induces endothelial cell apoptosis.
Mohanraj Dhanabal,Ramani Ramchandran,Matthew J.F. Waterman,Hua Lu,Bertrand Knebelmann,Mark S. Segal,Vikas P. Sukhatme +6 more
TL;DR: Analysis of the mechanism of endostatin action on endothelial cells and nonendothelial cells provides important mechanistic insight into endstatin action.
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X-linked Alport Syndrome Natural History in 195 Families and Genotype- Phenotype Correlations in Males
Jean-Philippe Jais,Bertrand Knebelmann,Iannis Giatras,Mario De Marchi,Gianfranco Rizzoni,Alessandra Renieri,Manfred Weber,Oliver Gross,Kai-Olaf Netzer,Frances Flinter,Yves Pirson,Christine Verellen,Jörgen Wieslander,Ulf Persson,Karl Tryggvason,Paula Martin,Jens Michael Hertz,Cornelis H. Schröder,Marek Sanak,Sarka Krejcova,Maria Fernanda Carvalho,Juan Saus,Corinne Antignac,Hubert J.M. Smeets,Marie Claire Gubler +24 more
TL;DR: The natural history of X-linked AS and correlations with COL4A5 mutations have been established in a large cohort of male patients and these data could be used for further evaluation of therapeutic approaches.
Journal ArticleDOI
X-Linked Alport Syndrome: Natural History and Genotype-Phenotype Correlations in Girls and Women Belonging to 195 Families: A "European Community Alport Syndrome Concerted Action" study
Jean-Philippe Jais,Bertrand Knebelmann,Iannis Giatras,Mario De Marchi,Gianfranco Rizzoni,Alessandra Renieri,Manfred Weber,Oliver Gross,Kai-Olaf Netzer,Frances Flinter,Yves Pirson,Karin Dahan,Jörgen Wieslander,Ulf Persson,Karl Tryggvason,Paula Martin,Jens Michael Hertz,Cornelis H. Schröder,Marek Sanak,Maria Fernanda Carvalho,Juan Saus,Corinne Antignac,Hubert J.M. Smeets,Marie Claire Gubler +23 more
TL;DR: Because of the absence of genotype-phenotype correlation and the large intrafamilial phenotypic heterogeneity, early prognosis of the disease in X-linked Alport syndrome carriers remains moot.
Journal ArticleDOI
The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity.
Debabrata Mukhopadhyay,Bertrand Knebelmann,Herbert T. Cohen,Subbian Ananth,Vikas P. Sukhatme +4 more
TL;DR: Observations support a new mechanism for VHL-mediated transcriptional repression via a direct inhibitory action on Sp1 and suggest that loss of Sp1 inhibition may be important in the pathogenesis of von Hippel-Lindau disease and RCC.