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Bin Zheng
Researcher at Nanjing University
Publications - 10
Citations - 308
Bin Zheng is an academic researcher from Nanjing University. The author has contributed to research in topics: Force spectroscopy & Gene. The author has an hindex of 3, co-authored 7 publications receiving 80 citations.
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Journal ArticleDOI
N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2.
Fang Tian,Bei Tong,Liang Sun,Shengchao Shi,Bin Zheng,Zibin Wang,Xianchi Dong,Xianchi Dong,Peng Zheng +8 more
TL;DR: In this paper, the authors used a cell surface-binding assay, a kinetics study, a single-molecule technique, and a computational method to investigate the interaction between these RBD (mutations) and ACE2.
Posted ContentDOI
Mutation N501Y in RBD of Spike Protein Strengthens the Interaction between COVID-19 and its Receptor ACE2
TL;DR: Wang et al. as discussed by the authors combined cell surface binding assay, kinetics study, single-molecule technique, and computational method to investigate the interaction between these RBD (mutations) and ACE2.
Journal ArticleDOI
Verification of sortase for protein conjugation by single-molecule force spectroscopy and molecular dynamics simulations.
TL;DR: The use of sortase for protein conjugation is verified, and a longer linker with a higher glycine content should be used with caution, because of the high probability of a closed conformation.
Journal ArticleDOI
OaAEP1-Mediated Enzymatic Synthesis and Immobilization of Polymerized Protein for Single-Molecule Force Spectroscopy.
TL;DR: This study provides a useful strategy for polyprotein engineering and immobilization by developing an enzymatic methodology for constructing polymerized protein step by step in a rationally-controlled sequence.
Journal ArticleDOI
Exploration of Metal-Ligand Coordination Bonds in Proteins by Single-molecule Force Spectroscopy
TL;DR: It is shown that metalloprotein plays an essential role in many different biological processes and represents an indispensable protein subgroup and the knowledge of this subgroup is essential for the development of new drugs to treat cancer.