B
Björn Petersen
Researcher at Friedrich Loeffler Institute
Publications - 78
Citations - 1897
Björn Petersen is an academic researcher from Friedrich Loeffler Institute. The author has contributed to research in topics: Xenotransplantation & Somatic cell nuclear transfer. The author has an hindex of 20, co-authored 71 publications receiving 1548 citations.
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Development of a generally applicable morphokinetic algorithm capable of predicting the implantation potential of embryos transferred on Day 3
TL;DR: The algorithm presented here can be used independently of culture conditions and fertilization method and provides predictive power not surpassed by other published algorithms for ranking embryos according to their blastocyst formation potential.
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Knockdown of porcine endogenous retrovirus (PERV) expression by PERV-specific shRNA in transgenic pigs.
Britta Dieckhoff,Björn Petersen,Wilfried A. Kues,Reinhard Kurth,Heiner Niemann,Joachim Denner +5 more
TL;DR: RNA interference is a promising option to inhibit PERV transmission and may be associated with the transmission of porcine endogenous retroviruses during xenotransplantation using porcines cells, tissues or organs.
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Efficient production of multi-modified pigs for xenotransplantation by ‘combineering’, gene stacking and gene editing
Konrad Fischer,Simone Kraner-Scheiber,Björn Petersen,Beate Rieblinger,Anna Buermann,Tatiana Flisikowska,Krzysztof Flisikowski,Susanne Christan,Marlene Edlinger,Wiebke Baars,Mayuko Kurome,Valeri Zakhartchenko,Barbara Kessler,Elena Plotzki,Izabela Szczerbal,Marek Switonski,Joachim Denner,Eckhard Wolf,Reinhard Schwinzer,Heiner Niemann,Alexander Kind,Angelika Schnieke +21 more
TL;DR: Pigs generated by serial nuclear transfer are a major advance towards clinical porcine xenotransplantation and demonstrate that livestock engineering has come of age.
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Germline transgenic pigs by Sleeping beauty transposition in porcine zygotes and targeted integration in the pig genome
Wiebke Garrels,Lajos Mátés,Stephanie Holler,Anna Dalda,Ulrike Taylor,Björn Petersen,Heiner Niemann,Zsuzsanna Izsvák,Zsuzsanna Izsvák,Zoltán Ivics,Zoltán Ivics,Wilfried A. Kues +11 more
TL;DR: Transposase-catalyzed transgenesis in a large mammalian species expands the arsenal of transgenic technologies for use in domestic animals and will facilitate the development of large animal models for human diseases.
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Isolation of murine and porcine fetal stem cells from somatic tissue.
TL;DR: F fetal somatic explants contain a subpopulation of somatic stem cells (FSSCs), which can be induced to display features of lineage-uncommitted stem cells, which might form a new source of stem cells useful in somatic nuclear transfer and cell therapy.