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Blanche Capel
Researcher at Duke University
Publications - 152
Citations - 18566
Blanche Capel is an academic researcher from Duke University. The author has contributed to research in topics: Gonad & Testis determining factor. The author has an hindex of 63, co-authored 146 publications receiving 16855 citations. Previous affiliations of Blanche Capel include National Institute for Medical Research & Fox Chase Cancer Center.
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Journal ArticleDOI
Disruption of Testis Cords by Cyclopamine or Forskolin Reveals Independent Cellular Pathways in Testis Organogenesis
Humphrey H.-C. Yao,Blanche Capel +1 more
TL;DR: Although formation of testis cords and development of other cell types normally take place in a tightly regulated sequence, each of these events can occur independent of the others.
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Peritubular Myoid Cells Are Not the Migrating Population Required for Testis Cord Formation in the XY Gonad
TL;DR: The results indicate that αSma-EYFP cells do not migrate into the gonad during the critical window of sex determination and cannot be the migrating cell type required for testis cord formation.
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Long- and short-lived murine hematopoietic stem cell clones individually identified with retroviral integration markers.
TL;DR: The results suggest that THSC clones are not all long-lived and that even the longest-lived ones may not be potentially immortal, and indicates the desirability of introducing multiple clones in therapeutic transplants.
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Estrogen represses SOX9 during sex determination in the red-eared slider turtle Trachemys scripta
Lindsey Barske,Blanche Capel +1 more
TL;DR: It is suggested that endogenous estrogen feminizes the medulla of the bipotential turtle gonad by inhibiting SOX9 expression, which may be involved in the male-to-female sex reversal in wild populations exposed to environmental estrogens.
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Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning
TL;DR: A pathway that integrates initiation of vascular development and testis cord morphogenesis, and lead to a model in which undifferentiated mesenchyme recruits blood vessels, proliferates in response, and performs a primary function in the morphogenesis and patterning of the developing organ is suggested.