B
Bo Yang
Researcher at Wuhan University
Publications - 14
Citations - 1090
Bo Yang is an academic researcher from Wuhan University. The author has contributed to research in topics: Alternative splicing & RNA splicing. The author has an hindex of 9, co-authored 12 publications receiving 859 citations. Previous affiliations of Bo Yang include Centre national de la recherche scientifique & Chinese Academy of Sciences.
Papers
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Journal ArticleDOI
MicroRNA Directly Enhances Mitochondrial Translation during Muscle Differentiation
Xiaorong Zhang,Xinxin Zuo,Bo Yang,Zongran Li,Yuanchao Xue,Yu Zhou,Jie Huang,Xiaolu Zhao,Jie Zhou,Yun Yan,Huiqiong Zhang,Peipei Guo,Hui Sun,Lin Guo,Yi Zhang,Xiang-Dong Fu,Xiang-Dong Fu +16 more
TL;DR: It is reported that miR-1, a microRNA specifically induced during myogenesis, efficiently enters the mitochondria where it unexpectedly stimulates, rather than represses, the translation of specific mitochondrial genome-encoded transcripts.
Journal ArticleDOI
Mechanisms for U2AF to define 3′ splice sites and regulate alternative splicing in the human genome
Changwei Shao,Bo Yang,Bo Yang,Tongbin Wu,Jie Huang,Peng Tang,Yu Zhou,Jie Zhou,Jinsong Qiu,Li Jiang,Hairi Li,Geng Chen,Hui Sun,Yi Zhang,Alain Denise,Dong-Er Zhang,Xiang-Dong Fu,Xiang-Dong Fu +17 more
TL;DR: It is reported that U2AF has the capacity to directly define ~88% of functional 3′ splice sites in the human genome, but numerous U2 AF binding events also occur in intronic locations.
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NEAT1 scaffolds RNA-binding proteins and the Microprocessor to globally enhance pri-miRNA processing.
Li Jiang,Changwei Shao,Changwei Shao,Qi-Jia Wu,Geng Chen,Jie Zhou,Bo Yang,Hairi Li,Lan-Tao Gou,Yi Zhang,Yangming Wang,Gene W. Yeo,Yu Zhou,Xiang-Dong Fu,Xiang-Dong Fu +14 more
TL;DR: A 'bird nest' model is suggested in which an lncRNA orchestrates efficient processing of potentially an entire class of small noncoding RNAs in the nucleus, to globally enhance pri-miRNA processing by the Drosha–DGCR8 Microprocessor.
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Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation.
Rui Xiao,Peng Tang,Bo Yang,Jie Huang,Yu Zhou,Changwei Shao,Hairi Li,Hui Sun,Yi Zhang,Xiang-Dong Fu,Xiang-Dong Fu +10 more
TL;DR: Findings exemplify hnRNP U/SAF-A as a potent regulator of nuclear ribonucleoprotein particles in diverse gene expression pathways by suggesting a general rule for splice site selection through modulating the core splicing machinery.
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Hepatitis B Viral RNA Directly Mediates Down-regulation of the Tumor Suppressor MicroRNA miR-15a/miR-16-1 in Hepatocytes
TL;DR: Evidence is presented that the microRNA machinery serves as a defense system against HBV infection, which, in turn, reprograms the expression of specific microRNAs in a manner that contributes to HCC development in HBV-infected cells.