B
Brett G. Jeffrey
Researcher at National Institutes of Health
Publications - 67
Citations - 1952
Brett G. Jeffrey is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Electroretinography & Retinal. The author has an hindex of 22, co-authored 55 publications receiving 1607 citations. Previous affiliations of Brett G. Jeffrey include Oregon Health & Science University & Oregon National Primate Research Center.
Papers
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Journal ArticleDOI
TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells
Catherine W. Morgans,J. Zhang,Brett G. Jeffrey,Steve M. Nelson,Neal S. Burke,Robert M. Duvoisin,R. Lane Brown +6 more
TL;DR: Identification of TRPM1 as a mGluR6-coupled cation channel reveals a key step in vision, expands the role of the TRP channel family in sensory perception, and presents insights into the evolution of vertebrate vision.
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The role of docosahexaenoic acid in retinal function
Brett G. Jeffrey,Harrison S. Weisinger,Harrison S. Weisinger,Martha Neuringer,Drake C. Mitchell +4 more
TL;DR: The focus of this review is on recent research that has sought to elucidate the role of DHA in retinal function, particularly within the rod photoreceptor outer segments where DHA is found at its highest concentration.
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Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery.
Catherine A Cukras,Henry E. Wiley,Brett G. Jeffrey,H. Nida Sen,Amy Turriff,Yong Zeng,Camasamudram Vijayasarathy,Dario Marangoni,Lucia Ziccardi,Sten Kjellstrom,Tae Kwon Park,Suja Hiriyanna,J. Fraser Wright,Peter Colosi,Zhijian Wu,Ronald A. Bush,Lisa L. Wei,Paul A. Sieving +17 more
TL;DR: The investigational product was generally well tolerated in all but one individual, and systemic antibodies against AAV8 increased in a dose-related fashion, but no antibodies against RS1 were observed.
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A randomized trial of different ratios of linoleic to α-linolenic acid in the diet of term infants: effects on visual function and growth
TL;DR: Lowering the LA:ALA in formula from 10:1 to 5:1 by using low-erucic acid canola oil resulted in a modest increase in plasma DHA but had no effect on VEP acuity or growth rate.
Journal ArticleDOI
ISCEV Standard for full-field clinical electroretinography (2022 update)
A. Robson,Laura J. Frishman,John R. Grigg,Ruth Hamilton,Brett G. Jeffrey,Mineo Kondo,Shiying Li,Daphne L. McCulloch +7 more
TL;DR: The International Society for Clinical Electrophysiology of Vision (ISCEV) presented an updated and revised ISCEV standard for clinical ERG testing as discussed by the authors , which includes minimum protocols for basic ERG stimuli, recording methods and reporting.