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Brian G. Trewyn

Researcher at Colorado School of Mines

Publications -  104
Citations -  14949

Brian G. Trewyn is an academic researcher from Colorado School of Mines. The author has contributed to research in topics: Mesoporous silica & Catalysis. The author has an hindex of 40, co-authored 101 publications receiving 13840 citations. Previous affiliations of Brian G. Trewyn include United States Department of Energy & Iowa State University.

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A mesoporous silica nanosphere-based carrier system with chemically removable CdS nanoparticle caps for stimuli-responsive controlled release of neurotransmitters and drug molecules.

TL;DR: An MCM-41 type mesoporous silica nanosphere-based controlled-release delivery system has been synthesized and characterized using surface-derivatized cadmium sulfide nanocrystals as chemically removable caps to encapsulate several pharmaceutical drug molecules and neurotransmitters inside the organically functionalized MSN Mesoporous framework.
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Mesoporous silica nanoparticles for drug delivery and biosensing applications

TL;DR: Recent research progress on the design of functional MSN materials with various mechanisms of controlled release, along with the ability to achieve zero release in the absence of stimuli, and the introduction of new characteristics to enable the use of nonselective molecules as screens for the construction of highly selective sensor systems are reviewed.
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Mesoporous silica nanoparticles deliver DNA and chemicals into plants

TL;DR: A honeycomb mesoporous silica nanoparticle system with 3-nm pores that can transport DNA and chemicals into isolated plant cells and intact leaves and capped the ends with gold nanoparticles to keep the molecules from leaching out is shown.
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Synthesis and functionalization of a mesoporous silica nanoparticle based on the sol-gel process and applications in controlled release.

TL;DR: Mesoporous silica nanoparticles are introduced as chemically and thermally stable nanomaterials with well-defined and controllable morphology and porosity and are proposed as the basis of nanodevices for the controlled release of drugs and genes into living cells.