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Brigitte Scolari
Researcher at University of Fribourg
Publications - 4
Citations - 77
Brigitte Scolari is an academic researcher from University of Fribourg. The author has contributed to research in topics: Innate immune system & Cytotoxic T cell. The author has an hindex of 3, co-authored 3 publications receiving 51 citations.
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Journal ArticleDOI
Interactions of human microglia cells with Japanese encephalitis virus.
Nils Lannes,Viviane Neuhaus,Brigitte Scolari,Solange Kharoubi-Hess,Michael Walch,Artur Summerfield,Luis Filgueira +6 more
TL;DR: Human microglia may be a source of neuronal infection and sustain JEV brain pathogenesis, and the role of these cells in viral transmission to susceptible cells is explored.
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γδ T Cells Kill Plasmodium falciparum in a Granzyme- and Granulysin-Dependent Mechanism during the Late Blood Stage.
Maria Andrea Hernández-Castañeda,Katharina Happ,Filippo Cattalani,Alexandra Wallimann,Marianne Blanchard,Isabelle Fellay,Brigitte Scolari,Nils Lannes,Smart Mbagwu,Benoît Fellay,Luis Filgueira,Pierre-Yves Mantel,Michael Walch +12 more
TL;DR: Overall, these data establish a granzyme- and granulysin-mediated innate immune mechanism exerted by γδ T cells to kill late-stage blood-residing P. falciparum.
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Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis.
Franziska Theilig,Anne Kathrin Enke,Brigitte Scolari,Danny Polzin,Sebastian Bachmann,Robert Koesters +5 more
TL;DR: Findings shown that tubular HIF-α stabilization in glomerular disease is beneficial for disease outcome, and in comparison with VHL knockout alone, GN is a much stronger activator of fibrosis such that stimuli other than hypoxia may be considered important for renal disease progression.
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Validation of Effective Extracellular Vesicles Isolation Methods Adapted to Field Studies in Malaria Endemic Regions
M. Zoia,Bibin Yesodha Subramanian,Klara K. Eriksson,Meera Sruthi Ravi,Shekoofeh Yaghmaei,Isabelle Fellay,Brigitte Scolari,Michael Walch,Pierre-Yves Mantel +8 more
TL;DR: Two protocols for EV isolation from cell culture supernatants, rodent and human plasma are established and validated and it is proposed that both of these approaches can be used in resource limited countries, therefore further helping to close the gap in knowledge of EVs during malaria.