Brooke A. LaFlamme

TL;DR: Recent identification of insect SFPs is reviewed and the multiple roles these proteins play in the postmating processes of female insects are discussed.

TL;DR: Evidence that a protease cascade acts in the seminal fluid of Drosophila during and after mating is presented and this results point to an important role for proteolysis among insect SFPs and suggest that protease cascades may be a mechanism for precise temporal regulation of multiple post-mating responses in females.

TL;DR: This review provides an overview of the identification of proteolysis regulators in the seminal fluid of humans and Drosophila melanogaster, the two species with the most comprehensively known seminal fluid proteomes and makes broad suggestions for the direction of future research.

TL;DR: The roles played by seminal fluid proteins (Sfps) in molecular social interactions between males and females of the fruit fly Drosophila melanogaster are reviewed, with a discussion of the ways in which Sfps can both shape and be shaped by the organismal-level social interactions in which they are involved.

TL;DR: This study identifies several classes of candidate seminal fluid proteins not previously documented in the D. melanogaster male ejaculate, including metabolic enzymes, nutrient transport proteins, and clotting factors, and defines 29 SFPs that are conserved despite >40 million years of Drosophila evolution.