B
Bruce Binkowitz
Researcher at Merck & Co.
Publications - 34
Citations - 1631
Bruce Binkowitz is an academic researcher from Merck & Co.. The author has contributed to research in topics: Finasteride & Clinical trial. The author has an hindex of 15, co-authored 34 publications receiving 1551 citations. Previous affiliations of Bruce Binkowitz include Brigham and Women's Hospital & University of Vienna.
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Journal ArticleDOI
Finasteride in the treatment of men with androgenetic alopecia
Keith D. Kaufman,Elise A. Olsen,David A. Whiting,Ronald C. Savin,Richard L. DeVillez,Wilma F. Bergfeld,Vera H. Price,Dominique Van Neste,Janet L. Roberts,Maria K. Hordinsky,Jerry Shapiro,Bruce Binkowitz,Glenn J. Gormley +12 more
TL;DR: In men with male pattern hair loss, finasteride 1 mg/d slowed the progression of hair loss and increased hair growth in clinical trials over 2 years.
Journal ArticleDOI
The effect of finasteride in men with benign prostatic hyperplasia
Gormley Glenn J,Elizabeth Stoner,Reginald C. Bruskewitz,Julianne Imperato-McGinley,Patrick C. Walsh,John D. McConnell,Gerald L. Andriole,Jack Geller,Bruce Bracken,Joyce S. Tenover,E. Darracott Vaughan,Frances Pappas,Alice Taylor,Bruce Binkowitz,Jennifer Ng +14 more
TL;DR: The treatment of benign prostatic hyperplasia with 5 mg of finasteride per day results in a significant decrease in symptoms of obstruction, an increase in urinary flow, and a decrease in prostatic volume, but at a slightly increased risk of sexual dysfunction.
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Clinical dose ranging studies with finasteride, a type 2 5α-reductase inhibitor, in men with male pattern hair loss
Janet L. Roberts,Virginia C. Fiedler,Julianne Imperato-McGinley,David A. Whiting,Elise A. Olsen,Jerome L. Shupack,Dowling B. Stough,Richard L. DeVillez,Robert L. Rietschel,Ronald C. Savin,Wilma F. Bergfeld,James M. Swinehart,Toni Funicella,Maria K. Hordinsky,Nicholas J. Lowe,Irving Katz,Anne W. Lucky,Lynn A. Drake,Vera H. Price,Darryl Weiss,Elizabeth Whitmore,Larry E. Millikan,Sigfrid A. Muller,Christopher Gencheff,Patrick R. Carrington,Bruce Binkowitz,Paul Kotey,Weili He,Karen Bruno,Carol A. Jacobsen,Lisa Terranella,Glenn J. Gormley,Keith D. Kaufman +32 more
TL;DR: Finasteride 1 mg/day is the optimal dose for the treatment of men with male pattern hair loss and was subsequently identified for further clinical development.
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Using Repeated Measures of Symptom Score, Uroflowmetry and Prostate Specific Antigen in the Clinical Management of Prostate Disease
Michael J. Barry,Cynthia J. Girman,Michael P. O'Leary,Elizabeth Walker-Corkery,Bruce Binkowitz,Abraham T.K. Cockett,Harry A. Guess +6 more
TL;DR: Clinicians can use data from 2 clinical trials to help interpret repeated measures of these variables in patients, and can consider obtaining paired measurements to decrease the effect of chance variation when they plan on following them over time.
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Design of the DEFINE trial: Determining the EFficacy and Tolerability of CETP INhibition with AnacEtrapib
Christopher P. Cannon,Hayes M. Dansky,Michael H. Davidson,Antonio M. Gotto,Eliot A. Brinton,A. Lawrence Gould,Michael Stepanavage,Sherry Xueyu Liu,Sukrut Shah,Joseph Rubino,Patrice H. Gibbons,Anne Hermanowski-Vosatka,Bruce Binkowitz,Yale B. Mitchel,Philip J. Barter +14 more
TL;DR: Determining the EFficacy and Tolerability of CETP INhibition with AnacEtrapib is a randomized, double-blind, placebo-controlled trial to assess the efficacy and safety profile of anacetrapib in patients with coronary heart disease (CHD) or CHD risk equivalents.