B
Bruce E. Johnson
Researcher at National Institutes of Health
Publications - 47
Citations - 6645
Bruce E. Johnson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 32, co-authored 47 publications receiving 6557 citations. Previous affiliations of Bruce E. Johnson include Uniformed Services University of the Health Sciences.
Papers
More filters
Journal ArticleDOI
A cell cycle regulator potentially involved in genesis of many tumor types
Alexander Kamb,Nelleke A. Gruis,Jane Weaver-Feldhaus,Qingyun Liu,Keith D Harshman,Sean V. Tavtigian,Elisabeth Stockert,Rufus S. Day,Bruce E. Johnson,Mark H. Skolnick,Mark H. Skolnick +10 more
TL;DR: Findings suggest that MTS1 mutations are involved in tumor formation in a wide range of tissues.
Journal ArticleDOI
Molecular analysis of the short arm of chromosome 3 in small-cell and non-small-cell carcinoma of the lung.
Hiltrud Brauch,Bruce E. Johnson,J Hovis,T Yano,Adi F. Gazdar,O S Pettengill,S Graziano,G D Sorenson,Bernard J. Poiesz,John D. Minna +9 more
TL;DR: It is concluded that loss of alleles at 3p is a change found consistently in small-cell lung carcinoma and occasionally in non-small-cell Lung carcinoma.
Journal ArticleDOI
Chemosensitivity testing of human lung cancer cell lines using the MTT assay.
J. Carmichael,James B. Mitchell,William DeGraff,Janet Gamson,Adi F. Gazdar,Bruce E. Johnson,Eli Glatstein,John D. Minna +7 more
TL;DR: This panel of lung cancer cells exhibited a drug sensitivity profile paralleling that observed in clinical practice, suggesting that this lung cancer cell line panel in combination with a relatively simple but reproducible chemosensitivity assay, such as the MTT assay, has potential for the testing of drug combinations and evaluating new anti-cancer agents in vitro.
Journal Article
Characteristics of Cell Lines Established from Human Colorectal Carcinoma
Jae-Gahb Park,Herbert K. Oie,Paul H. Sugarbaker,Jerry G. Henslee,Tchaw-Ren Chen,Bruce E. Johnson,Adi F. Gazdar +6 more
TL;DR: A high incidence of amplification of one or more as yet unidentified genes is found in human colorectal carcinoma cell lines established from primary and metastatic sites by us during the years 1982 to 1985.
Journal Article
Characteristics of Cell Lines Established from Human Gastric Carcinoma
Jae-Gahb Park,Jae-Gahb Park,Harold Frucht,Renato V. Larocca,David P. Bliss,Yukio Kurita,Tchaw Ren Chen,Jerry G. Henslee,Jane B. Trepel,Robert T. Jensen,Bruce E. Johnson,Young Jue Bang,Jin Pok Kim,Adi F. Gazdar +13 more
TL;DR: The four well characterized cell lines reported should provide useful additions to the modest number currently available for in vitro studies of gastric carcinoma, and their properties are remarkably similar to those found in the panel of colorectal carcinoma cell lines.