Bruce R. Newton

TL;DR: A real-time reverse transcription–polymerase chain reaction (RT-PCR) assay was developed to rapidly detect the severe acute respiratory syndrome–associated coronavirus (SARS-CoV) and proved suitable to detect SARS- coV in clinical specimens.

TL;DR: During the 2001 anthrax outbreak, a highly sensitive and specific three-target (two plasmid and one chromosomally located target) 5´ nuclease assay (real-time polymerase chain reaction [PCR]) for detection and identification of Bacillus anthracis was evaluated and validated.

TL;DR: Results using a DNA vaccine expressing a fusion of the measles hemagglutinin (H) protein and the complement component, C3d, to enhance the titers of neutralizing antibody indicated that immunizations with the DNA expressing sH-3C3d had higher titer of anti-H antibodies compared to serum from mice vaccinated with DNA expresses sH only.

TL;DR: It was found that subjecting spores at a concentration of 107 CFU/ml to a dose of 2.5 × 106 rads resulted in a 6-log-unit reduction of spore viability, and clinical and public health laboratories which test specimens for B. anthracis could potentially incorporate gamma irradiation into sample processing protocols without compromising the sensitivity of the B. Anthracis assays.

TL;DR: This report presents the first molecular epidemiological study of circulating wild‐type measles viruses in Morocco, and shows that all the viruses were closely related to each other and were members of genotype C2.