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Bruce S. Edwards
Researcher at University of New Mexico
Publications - 132
Citations - 7240
Bruce S. Edwards is an academic researcher from University of New Mexico. The author has contributed to research in topics: Receptor & Natural killer cell. The author has an hindex of 37, co-authored 131 publications receiving 6904 citations. Previous affiliations of Bruce S. Edwards include University of Wisconsin-Madison.
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Journal ArticleDOI
On-Chip Interconnection Architecture of the Tile Processor
David Wentzlaff,Patrick Robert Griffin,Henry Hoffmann,Liewei Bao,Bruce S. Edwards,Carl Ramey,Matthew Mattina,Chyi-Chang Miao,J.F. Brown,Anant Agarwal +9 more
TL;DR: IMesh, the tile processor architecture's on-chip interconnection network, connects the multicore processor's tiles with five 2D mesh networks, each specialized for a different use, taking advantage of the C-based ILIB interconnection library.
Journal ArticleDOI
Virtual and biomolecular screening converge on a selective agonist for GPR30
Cristian Bologa,Chetana M. Revankar,Susan M. Young,Bruce S. Edwards,Jeffrey B. Arterburn,Alexander S. Kiselyov,Matthew A. Parker,Sergey E. Tkachenko,Nikolay P. Savchuck,Larry A. Sklar,Tudor I. Oprea,Eric R. Prossnitz +11 more
TL;DR: The identification of the first G PR30-specific agonist, G-1 (1), capable of activating GPR30 in a complex environment of classical and new estrogen receptors is described.
Processor: A 64-Core SoC with Mesh Interconnect
Shane L. Bell,Bruce S. Edwards,John Amann,Rich Conlin,Kevin Joyce,Vince Leung,John MacKay,Mike Reif,Liewei Bao,J.F. Brown,Matthew Mattina,Chyi-Chang Miao,Carl Ramey,David Wentzlaff,Walker Anderson,Ethan Berger,Nat Fairbanks,Durlov Khan,Froilan Montenegro,Jay Stickney,John Zook +20 more
TL;DR: The TILE64TM processor as mentioned in this paper is a multicore SoC targeting the high-performance demands of a wide range of embedded applications across networking and digital multimedia applications, with 64 tile processors arranged in an 8x8 array.
Proceedings ArticleDOI
TILE64 - Processor: A 64-Core SoC with Mesh Interconnect
Shane L. Bell,Bruce S. Edwards,John Amann,Richard Conlin,Kevin Joyce,V. Leung,J. MacKay,M. Reif,Liewei Bao,J.F. Brown,Matthew Mattina,Chyi-Chang Miao,Carl Ramey,David Wentzlaff,W. Anderson,E. Berger,N. Fairbanks,D. Khan,F. Montenegro,J. Stickney,J. Zook +20 more
TL;DR: The TILE64TM processor is a multicore SoC targeting the high-performance demands of a wide range of embedded applications across networking and digital multimedia applications.
Journal ArticleDOI
Selective Chemical Inhibition of agr Quorum Sensing in Staphylococcus aureus Promotes Host Defense with Minimal Impact on Resistance
Erin K. Sully,Natalia Malachowa,Bradley O. Elmore,Susan M. Alexander,Jon Femling,Brian M. Gray,Frank R. DeLeo,Michael Otto,Ambrose L. Cheung,Bruce S. Edwards,Larry A. Sklar,Alexander R. Horswill,Pamela R. Hall,Hattie D. Gresham +13 more
TL;DR: Savirin was efficacious in two murine skin infection models, abating tissue injury and selectively promoting clearance of agr+ but not Δagr bacteria when administered at the time of infection or delayed until maximal abscess development, and chemical inhibitors can selectively target AgrA in S. aureus to promote host defense while sparing agr signaling.