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Bryan E. Landen
Researcher at Eli Lilly and Company
Publications - 2
Citations - 163
Bryan E. Landen is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Substrate (chemistry) & Adsorption. The author has an hindex of 2, co-authored 2 publications receiving 161 citations.
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Journal ArticleDOI
Large-scale stereoselective enzymatic ketone reduction with in situ product removal via polymeric adsorbent resins
Jeffrey Thomas Vicenzi,Milton J. Zmijewski,Reinhard Matthew Robert,Bryan E. Landen,Muth William Lawrence,Paul G. Marler +5 more
TL;DR: The NAD(P)H-dependent enzymatic activity within living Zygosaccharomyces rouxii was utilized to accomplish this reaction and the reaction was scaled-up to a volume of 300 l by utilizing a commercially available agitated filter as a reactor.
Journal ArticleDOI
Leptin is a four-helix bundle: secondary structure by NMR
Allen D Kline,Gerald W. Becker,Lisa M. Churgay,Bryan E. Landen,Debra K Martin,Muth William Lawrence,Radhakrishnan Rathnachalam,John M. Richardson,Brigitte Elisabeth Schoner,Maverick Ulmer,John E. Hale +10 more
TL;DR: Backbone NMR signals for mouse leptin (13C/15N ‐labeled) have been assigned and its secondary structure reveals it to be a four‐helix bundle cytokine, in agreement with leptin as a member of the short-helix cytokine family.