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Byunghee Koh
Researcher at Indiana University
Publications - 23
Citations - 648
Byunghee Koh is an academic researcher from Indiana University. The author has contributed to research in topics: Transcription factor & Cellular differentiation. The author has an hindex of 12, co-authored 20 publications receiving 477 citations. Previous affiliations of Byunghee Koh include Indiana University – Purdue University Indianapolis & Sogang University.
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Journal ArticleDOI
HHQ and PQS, two Pseudomonas aeruginosa quorum-sensing molecules, down-regulate the innate immune responses through the nuclear factor-κB pathway
Kiwan Kim,Young Uk Kim,Byunghee Koh,Soo Seok Hwang,Seol-Hee Kim,François Lépine,You-Hee Cho,Gap Ryol Lee +7 more
TL;DR: The results suggest that HHQ and PQS produced by P. aeruginosa actively suppress host innate immune responses, and this effect was mediated through the NF‐κB pathway.
Journal ArticleDOI
Th2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthma
Byunghee Koh,Soo Seok Hwang,Joo Young Kim,Wonyong Lee,Min-Jong Kang,Chun Geun Lee,Jung Won Park,Richard A. Flavell,Richard A. Flavell,Gap Ryol Lee,Gap Ryol Lee +10 more
TL;DR: The results directly demonstrate that the Th2 LCR is critically important in the regulation of Th2 cytokine genes, in chromatin remodeling of the Th1 cytokine locus, and in the pathogenesis of allergic asthma.
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Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation.
Soo Seok Hwang,Young Uk Kim,Sumin Lee,Sung Woong Jang,Minkyung Kim,Byunghee Koh,Wonyong Lee,Joomyeong Kim,Abdallah Souabni,Meinrad Busslinger,Gap Ryol Lee +10 more
TL;DR: It is discovered that transcription factor YY1 bound to the LCR and the entire Th2 cytokine locus in a Th2-specific manner and is required for regulation of the Th2 influenza locus and Th2 cell differentiation.
Journal ArticleDOI
T follicular regulatory cells and IL-10 promote food antigen–specific IgE
Markus M. Xie,Qiang Chen,Hong Liu,Kai Yang,Byunghee Koh,Hao Wu,Soheila J. Maleki,Barry K. Hurlburt,Joan M. Cook-Mills,Mark H. Kaplan,Alexander L. Dent +10 more
TL;DR: It is revealed that TFR cells have an unexpected helper role in promoting food allergy and are a novel target for drug development.
Journal ArticleDOI
The ETS Family Transcription Factors Etv5 and PU.1 Function in Parallel To Promote Th9 Cell Development.
Byunghee Koh,Matthew M. Hufford,Duy Pham,Matthew R. Olson,Tong Wu,Rukhsana Jabeen,Xin Sun,Mark H. Kaplan +7 more
TL;DR: It is demonstrated that the ETS transcription factor ETS variant 5 (ETV5) promotes IL-9 production in Th9 cells by binding and recruiting histone acetyltransferases to the Il9 locus at sites distinct from PU.1.