C. C.-W. Yu

TL;DR: Data suggest that in normal tissues and lymphoid neoplasms, PCNA immunolocalization can be used as an index of cell proliferation, however, in some forms of neoplasia, including breast and gastric cancer and in vitro cell lines, the simple relation between PCNA expression and cell proliferation is lost.

TL;DR: Staining with PC10 may be of particular value in the identification of patients at greatest risk of rapid tumour metastasis and early death in cases of haemangiopericytoma.

TL;DR: Both PCNA immunostaining and AgNOR counts were found to correlate well with histological grading and all three methods independently showed good correlations with survival, suggesting that these proliferation‐associated markers may be used as additional features to support Histological grading in this relatively uncommon group of tumours.

TL;DR: Positive staining for p53, not detectable in normal cells because wild‐type p53 is rapidly degraded, reflects abnormal stabilization of p53 protein, and in many cases suggests p53 gene mutation.

TL;DR: In this article, an immunohistochemical study employing CM-1, an antiserum raised against recombinant human p53 protein, was conducted on 77 cutaneous melanocytic lesions and five lymph node metastases from malignant melanoma.