C
C D Allis
Researcher at Pennsylvania State University
Publications - 2
Citations - 1564
C D Allis is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Nucleosome & Histone code. The author has an hindex of 2, co-authored 2 publications receiving 1497 citations.
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Journal ArticleDOI
Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.
Patrick A. Grant,Laura J. Duggan,Jacques Côté,S M Roberts,James E. Brownell,Reyes Candau,Reiko Ohba,Tom Owen-Hughes,C D Allis,Fred Winston,Shelley L. Berger,Jerry L. Workman +11 more
TL;DR: The function of Gcn5 as a hist one acetyltransferase within the Ada and SAGA adaptor complexes indicates the importance of histone acetylation during steps in transcription activation mediated by interactions with transcription activators and general transcription factors.
Journal ArticleDOI
Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro.
Michelle Vettese-Dadey,Patrick A. Grant,T R Hebbes,C Crane Robinson,C D Allis,Jerry L. Workman +5 more
TL;DR: Data show that USF and GAL4‐AH preferentially interact with nucleosome cores containing highly acetylated histone H4, which appears to play a primary role in the structural changes that mediate enhanced binding of transcription factors to their recognition sites within nucleosomes.