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C. J. M. Aarsman
Researcher at Utrecht University
Publications - 8
Citations - 475
C. J. M. Aarsman is an academic researcher from Utrecht University. The author has contributed to research in topics: Monoclonal antibody & Antibody. The author has an hindex of 7, co-authored 8 publications receiving 464 citations.
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Journal ArticleDOI
Low-dose N-Acetylcysteine Protects Rats against Endotoxin-mediated Oxidative Stress, But High-dose Increases Mortality
R. C. Sprong,A. M. L. Winkelhuyzen-Janssen,C. J. M. Aarsman,J. F. L. M. Van Oirschot,T. van der Bruggen,B. S. Van Asbeck +5 more
TL;DR: It is concluded that low-dose NAC protects against LPS toxicity by scavenging H2O2, while higher doses may have the opposite effect.
Journal ArticleDOI
Detection of Listeria monocytogenes in cheese with the magnetic immuno-polymerase chain reaction assay
Ad C. Fluit,Ruurd Torensma,M. J. C. Visser,C. J. M. Aarsman,Miriam J.J.G. Poppelier,Ben Keller,P. Klapwijk,Jan Verhoef +7 more
TL;DR: An improvement of the MIPA method was obtained by using a PCR step based on the listeriolysin O gene, which detected L. monocytogenes in three naturally contaminated cheese samples with two different MAbs and PCR primers specific for the gene encoding the delayed-hypersensitivity factor.
Journal ArticleDOI
Dimethylthiourea protects rats against gram-negative sepsis and decreases tumor necrosis factor and nuclear factor κB activity
TL;DR: The results suggest that the protective effect of DMTU in gram-negative bacterial sepsis may be the result of a reduction in TNF activity.
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Monoclonal antibodies that react with live Listeria spp.
Ruurd Torensma,M. J. C. Visser,C. J. M. Aarsman,Miriam J.J.G. Poppelier,Ad C. Fluit,Jan Verhoef +5 more
TL;DR: Marked differences were observed between the reactivities of MAbs as determined by a magnetic immunoluminescence assay and a whole-cell enzyme-linked immunosorbent assay.
Journal ArticleDOI
Monoclonal antibodies that detect live salmonellae.
Ruurd Torensma,M. J. C. Visser,C. J. M. Aarsman,Miriam J.J.G. Poppelier,R. Van Beurden,Ad C. Fluit,Jan Verhoef +6 more
TL;DR: Nine immunoglobulin G and M murine monoclonal antibody-producing hybridomas reactive with live Salmonella bacteria were obtained from several fusions of immune spleen cells and Sp2/0 myeloma cells and proved to be reactive with a distinct serotype.