M
Michael E. Berens
Researcher at Translational Genomics Research Institute
Publications - 207
Citations - 17396
Michael E. Berens is an academic researcher from Translational Genomics Research Institute. The author has contributed to research in topics: Glioma & Cancer. The author has an hindex of 61, co-authored 188 publications receiving 15125 citations. Previous affiliations of Michael E. Berens include Seoul National University & St. Joseph's Hospital and Medical Center.
Papers
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Journal ArticleDOI
Molecular classification of cutaneous malignant melanoma by gene expression profiling
M. Bittner,Paul S. Meltzer,Yi Chen,Yong-hui Jiang,E. A. Seftor,Mary J.C. Hendrix,Michael D. Radmacher,Richard M. Simon,Zohar Yakhini,Amir Ben-Dor,Amir Ben-Dor,Nick Sampas,Edward R. Dougherty,Ena Wang,Francesco M. Marincola,C. Gooden,John Lueders,Arthur A. Glatfelter,P.C.A. Pollock,John D. Carpten,E. Gillanders,D. Leja,K. Dietrich,Christian Beaudry,Michael E. Berens,David S. Alberts,Vernon K. Sondak,Nicholas K. Hayward,J.M. Trent +28 more
TL;DR: Many genes underlying the classification of this subset of melanomas are differentially regulated in invasive melanomas that form primitive tubular networks in vitro, a feature of some highly aggressive metastatic melanomas.
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Cost of Migration: Invasion of Malignant Gliomas and Implications for Treatment
TL;DR: In this paper, the authors discuss mechanisms of glioma invasion, characteristics of the invasive cell, and consequences of this cellular phenotype for surgical resection, oncologic treatments, and future perspectives for anti-invasive strategies.
Journal ArticleDOI
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
Vasanthi S. Viswanathan,Matthew J. Ryan,Harshil Dhruv,Shubhroz Gill,Ossia M. Eichhoff,Brinton Seashore-Ludlow,Samuel D. Kaffenberger,John K. Eaton,Kenichi Shimada,Andrew J. Aguirre,Andrew J. Aguirre,Srinivas R. Viswanathan,Srinivas R. Viswanathan,Shrikanta Chattopadhyay,Pablo Tamayo,Pablo Tamayo,Wan Seok Yang,Matthew G. Rees,Sixun Chen,Zarko V. Boskovic,Sarah Javaid,Cherrie Huang,Xiaoyun Wu,Yuen-Yi Tseng,Elisabeth Roider,Dong Gao,James M. Cleary,Brian M. Wolpin,Jill P. Mesirov,Jill P. Mesirov,Daniel A. Haber,Daniel A. Haber,Jeffrey A. Engelman,Jesse S. Boehm,Joanne Kotz,Cindy S. Hon,Yu Chen,William C. Hahn,William C. Hahn,Mitchell P. Levesque,John G. Doench,Michael E. Berens,Alykhan F. Shamji,Paul A. Clemons,Brent R. Stockwell,Stuart L. Schreiber,Stuart L. Schreiber,Stuart L. Schreiber +47 more
TL;DR: Vulnerability to ferroptic cell death induced by inhibition of a lipid peroxidase pathway as a feature of therapy-resistant cancer cells across diverse mesenchymal cell-state contexts is identified.
Journal ArticleDOI
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
Matthew J. Hangauer,Vasanthi S. Viswanathan,Matthew J. Ryan,Dhruv Bole,John K. Eaton,Alexandre Matov,Jacqueline Galeas,Harshil Dhruv,Michael E. Berens,Stuart L. Schreiber,Stuart L. Schreiber,Stuart L. Schreiber,Frank McCormick,Michael T. McManus +13 more
TL;DR: It is demonstrated that a similar therapy-resistant cell state underlies the behaviour of persister cells derived from a wide range of cancers and drug treatments, and it is suggested that targeting of GPX4 may represent a therapeutic strategy to prevent acquired drug resistance.
Journal ArticleDOI
Molecular mechanisms of glioma cell migration and invasion.
Tim Demuth,Michael E. Berens +1 more
TL;DR: In this review, the main features which may underlie the invasive phenotype of human gliomas are focused on, and offer a biological basis for optimism towards therapeutic advances to come.