Calvin C. Willhite

TL;DR: There is no consistent and convincing evidence to associate the Al found in food and drinking water at the doses and chemical forms presently consumed by people living in North America and Western Europe with increased risk for Alzheimer's disease (AD), and there is there clear evidence to show use of Al-containing underarm antiperspirants or cosmetics increases the risk of AD or breast cancer.

TL;DR: The results suggested that the other nitriles examined here possess little, if any, acute toxicity in the absence of normal hepatic function and that these nit riles were activated by hepatic mechanisms to release cyanide which can account for their major acute toxic effects.

TL;DR: In both rats and hamsters oral administration of the drug seemed to be more teratogenic than administration by other routes suggesting that metabolism of ribavirin in the maternal gastro-intestinal tract and/or liver may change it into its active form.

TL;DR: Medical problems associated with industrial or agricultural arsenicalism are most often typified by chronic exposure; future studies should emphasize those routes of administration and types of exposure that are characteristic of arsenic intoxication.

TL;DR: observed in the hamster induced exencephaly, encephalocoeles, and rib fusions and bifurcations in the offspring suggest that the teratogenic effects of both acrylonitrile and propionitrile are related to the metabolic release of cyanide