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Carl L. Schildkraut
Researcher at Albert Einstein College of Medicine
Publications - 82
Citations - 6489
Carl L. Schildkraut is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: DNA replication & Control of chromosome duplication. The author has an hindex of 44, co-authored 80 publications receiving 6131 citations. Previous affiliations of Carl L. Schildkraut include Yeshiva University.
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Journal ArticleDOI
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
Agnel Sfeir,Settapong T. Kosiyatrakul,Dirk Hockemeyer,Sheila L. MacRae,Jan Karlseder,Carl L. Schildkraut,Titia de Lange +6 more
TL;DR: The TTAGGG repeat arrays of mammalian telomeres pose a challenge to the DNA replication machinery, giving rise to replication-dependent defects that resemble those of aphidicolin-induced common fragile sites.
Journal ArticleDOI
Dependence of the melting temperature of DNA on salt concentration
TL;DR: These calculations support the hypothesis that the change of Tm with salt concentration is due to changes in the screened interactions between the fixed phosphate charges, and indicate some of the limitations of the theoretical model.
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The Epstein-Barr virus origin of plasmid replication, oriP, contains both the initiation and termination sites of DNA replication
Toni A. Gahn,Carl L. Schildkraut +1 more
TL;DR: The replicative forms generated by EBV oriP are examined using 2D gel electrophoresis and patterns obtained suggest that replication from oriP proceeds similarly in the viral genome.
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Replication program of active and inactive multigene families in mammalian cells.
TL;DR: These results provide the first molecular evidence that the coordinate timing of replication of contiguous sequences within a multigene family is a general property of the mammalian genome.
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Initiation and termination of DNA replication in human rRNA genes.
TL;DR: Termination of replication, the convergence of opposing replication forks, was found throughout the ribosomal DNA repeat units, and, in some repeats, specifically at the junction of the 3' end of the transcription unit and the NTS.