C
Carla A. Cummins
Researcher at Wellcome Trust Sanger Institute
Publications - 7
Citations - 4276
Carla A. Cummins is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 3, co-authored 3 publications receiving 2177 citations.
Papers
More filters
Journal ArticleDOI
Roary: Rapid large-scale prokaryote pan genome analysis
Andrew J. Page,Carla A. Cummins,Martin Hunt,Vanessa K. Wong,Sandra Reuter,Matthew T. G. Holden,Maria Fookes,Daniel Falush,Jacqueline A. Keane,Julian Parkhill +9 more
TL;DR: Roary, a tool that rapidly builds large-scale pan genomes, identifying the core and accessory genes, is introduced, making construction of the pan genome of thousands of prokaryote samples possible on a standard desktop without compromising on the accuracy of results.
Posted ContentDOI
Roary: Rapid large-scale prokaryote pan genome analysis
Andrew J. Page,Carla A. Cummins,Martin Hunt,Vanessa K. Wong,Sandra Reuter,Matthew T. G. Holden,Maria Fookes,Jacqueline A. Keane,Julian Parkhill +8 more
TL;DR: Roary is introduced, a tool that rapidly builds large-scale pan genomes, identifying the core and dispensable accessory genes and making construction of the pan genome of thousands of prokaryote samples possible on a standard desktop without compromising on the accuracy of results.
Journal ArticleDOI
The TraDIS toolkit: sequencing and analysis for dense transposon mutant libraries
Lars Barquist,Matthew Mayho,Carla A. Cummins,Amy K. Cain,Christine J. Boinett,Andrew J. Page,Gemma C. Langridge,Michael A. Quail,Jacqueline A. Keane,Julian Parkhill +9 more
TL;DR: An optimized high-yield library preparation and sequencing protocol for TraDIS experiments and a novel software pipeline for analysis of the resulting data are described.
Journal ArticleDOI
The European Nucleotide Archive in 2022
Josephine Burgin,Alisha Ahamed,Carla A. Cummins,Rajkumar Devraj,K. Gueye,Dipayan Sen Gupta,Vikas Gupta,Muhammad Haseeb,Maira Ihsan,Eugene Ivanov,Suran Jayathilaka,Vishnukumar Balavenkataraman Kadhirvelu,Manish Kumar,Ankur Lathi,Rasko Leinonen,Milena Mansurova,Jasmine McKinnon,Colman O'Cathail,Joana Paupério,Stephane Pesant,Nadim Rahman,Gabriele Rinck,S. Selvakumar,Swati Suman,Senthilnathan Vijayaraja,Zahra Waheed,Peter Woollard,David Yuan,Ahmad M-S Zyoud,Tony Burdett,Guy Cochrane +30 more
TL;DR: The European Nucleotide Archive (ENA) as discussed by the authors is an open and supported platform for the management, archiving, publication, and dissemination of data; and to the scientific community as a whole, it offers a globally comprehensive data set through a host of data discovery and retrieval tools.
Journal ArticleDOI
Identification of mutations in SARS-CoV-2 PCR primer regions
Anikó Mentes,Krisztián Papp,Dávid Visontai,József Stéger,István Csabai,Guy Cochrane,Nadim Rahman,Carla A. Cummins,David Yuan,S. Selvakumar,Milena Mansurova,Colman O'Cathail,Alexey Sokolov,Ross Thorne,Marion Koopmans,David F. Nieuwenhuijse,Bas Oude-Munnink,Nathalie Worp,Clara Amid,Anna Medgyes-Horváth,Orsolya Pipek +20 more
TL;DR: In this paper , the authors proposed an analysis pipeline to discover genomic variations overlapping the target regions of commonly used PCR primer sets and provided the list of these mutations in a publicly available format based on a dataset of more than 1.2 million SARS-CoV-2 samples.